Newborn Screening of the Endocrine System: Best Practices for Evaluation of Hypothyroidism and Congenital Adrenal Hyperplasia.

Newborn screening for congenital hypothyroidism (CH) and congenital adrenal hyperplasia (CAH) is essential to reduce the risk of morbidity and mortality from delayed identification and treatment of these conditions. Infants with untreated CH are at risk for intellectual disability, psychomotor dysfunction, and impaired growth, and those with untreated CAH are at risk for adrenal crisis as well as significant virilization of female infants. As multiple perinatal factors such as prematurity, clinical instability, and maternal health conditions and medications can impact newborn screening results, early consultation of pediatric endocrinology is recommended to ensure test interpretation incorporates perinatal considerations.

Severe multiple organ failure as a consequence of diabetic ketoacidosis in an adolescent with new-onset type 1 diabetes: A case report.

The initial presentation of pediatric diabetes is variable, making prompt diagnosis and treatment challenging. The overlap between type 1 and type 2 diabetes and presence of developmental delays can complicate diagnosis, resulting in delays and severe illness at presentation. Here we describe a case of a 13-year-old male with autism and attention deficit hyperactivity disorder who presented with severe diabetic ketoacidosis, multiple organ failure, and shock.

Pediatric Diabetes on the Rise: Trends in Incident Diabetes During the COVID-19 Pandemic.

Context: The effects of the coronavirus disease 2019 (COVID-19) pandemic on the incident cases of pediatric type 1 diabetes (T1D) and type 2 diabetes (T2D) are not clear.

Objective: To identify trends in incidence and presentation of pediatric new-onset T1D and T2D during the COVID-19 pandemic.

Methods: A retrospective chart review was conducted.

The Perfect Storm: Rapid Progression of Diabetic Ketoacidosis in Pediatric Diabetes in the Setting of COVID-19.

Objective: The coronavirus disease 2019 (COVID-19) pandemic has introduced countless challenges to the medical field. Although pediatric patients have been reported to have lower rates of COVID-19 mortality, the presence of pre-existing conditions can heighten the severity of their clinical presentation. This report discusses the potential influence COVID-19 might have on diabetic ketoacidosis.

DEPOT TRIAMCINOLONE INJECTION CONTRIBUTING TO ADRENAL SUPPRESSION AND CUSHING SYNDROME: CASE REPORT AND LITERATURE REVIEW.

Objective: To present an unusual case of Cushing syndrome in a pediatric patient caused by a single depot triamcinolone injection.

Methods: A case report followed by a literature review are presented.

Results: A 13-year-old male presented with rapid weight gain, elevated blood pressure, headaches, and diffuse purplish striae.