Fitting accuracy of preformed osteosynthesis plates for zygomaticomaxillary complex fractures.

Background: Preformed osteosynthesis plates are a novel treatment option for the fixation of zygomaticomaxillary complex (ZMC) fractures. A preformed plate may improve the reduction accuracy, as an accurate fit and sufficient fixation possibilities are provided.

Purpose: This study aimed to evaluate the virtual fitting accuracy of preformed anatomical osteosynthesis zygoma plates and to assess whether their shape and size are adequate for ZMC fracture treatment.

Soft-tissue prediction based on 3D photographs for virtual surgery planning of orthognathic surgery.

Objectives: In orthognathic surgery, preoperative three-dimensional soft-tissue simulations are frequently used to determine the desired jaw displacements to enhance the facial soft tissue. This study aimed to develop and validate a deep learning-based method to predict postoperative facial soft tissue outcomes in real time for various orthognathic procedures.

Methods: The study included 458 patients who underwent various orthognathic procedures.

Autophagy-enhancing strategies to promote intestinal viral resistance and mucosal barrier function in SARS-CoV-2 infection.

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of Coronavirus disease 19 (COVID-19), continues to circulate globally despite the widespread vaccination and therapeutics like Paxlovid, remdesivir, and molnupiravir. COVID-19 is associated with both respiratory and gastrointestinal manifestations, with persistent intestinal pathology contributing to the post-COVID-19 condition. We have previously demonstrated the antiviral activity of autophagy-blocking drugs, such as Berbamine dihydrochloride, against intestinal SARS-CoV-2 acquisition.

Splintless maxillomandibular advancement for edentulous sleep apnoea patients: surgical accuracy and efficacy.

The primary aim of this study was to assess the accuracy and predictability of a splintless treatment protocol for edentulous patients with moderate to severe obstructive sleep apnoea (OSA) undergoing maxillomandibular advancement (MMA). Ten consecutive edentulous patients treated with MMA were enrolled in this retrospective study. All cases were virtually planned, followed by computer-aided design of individual osteotomy cutting guides and patient-specific implants.

Accuracy of virtual surgical planning for segmental mandibular resections: A comparison of connected resection guides versus separate resection guides in a cadaver study.

Mandibular reconstruction after oncologic resection is challenging owing to functional and esthetic demands. Three-dimensional virtual surgical planning enhances surgical predictability and precision. This study compared separate versus connected mandibular resection guides, hypothesizing that connected guides achieve more precise alignment with the virtual surgical plan, thereby improving resection accuracy and reconstruction outcomes.