Increasing dietary palmitic and stearic acid decreases de novo synthesis of milk fatty acids in dairy cows based on modeling natural carbon isotope enrichment.

Background: Mammary de novo lipogenesis is dynamic but total lipogenesis is not easily quantified because palmitic acid is also available from dietary absorption.

Objective: The study aimed to quantify the effect of dietary palmitic and stearic levels on mammary de novo lipogenesis using natural C enrichment differences in ingredients.

Methods: Twelve mid-lactation Holstein cows were used in a 4 x 4 Latin square design with 21 d periods.

Brief group adaptation of the Unified Protocol for integrated primary care: Open trial of a transdiagnostic intervention delivered via telehealth.

There is a pressing need to scale up access to evidence-based mental health treatment. Offering transdiagnostic treatments that accommodate a variety of presenting concerns and comorbidities in integrated primary care settings via group format and telehealth modalities can help to efficiently increase access to care. To meet this need, we refined a brief group adaptation of the Unified Protocol for the transdiagnostic treatment of emotional disorders, called managing stress and emotions (MSE), which was modified for feasibility in integrated primary care settings and telehealth delivery.

The shortcomings of science at the point of care delivery: An editors' retrospective.

The editors feel so much gratitude for the opportunity that they had to witness, create, and develop published science. They absolutely loved working with hundreds of authors and seeing the fruition of their work, which they hope will be applied at the Point of Care delivery in practice settings for real-world impact. The editors feel indebted to so many partners in this work (see the Acknowledgments section).

Brief modular anxiety intervention for primary care: Hybrid I pilot randomized controlled trial of feasibility, acceptability, effectiveness, and implementation potential.

Background: Anxiety is highly prevalent, but undertreated, in primary care. Brief, non-pharmacological interventions are needed. Modular Anxiety Skills Training (MAST), a cognitive-behavioral anxiety intervention, was developed for primary care and tailored for a Veteran sample (MAST-V).