Evaluating micro-computed tomography for investigation of the pediatric hyoid-larynx complex.

Background: Conventional CT imaging has limitations in detecting subtle fractures or soft tissue hemorrhages of the pediatric hyoid-larynx complex due to its largely unossified, cartilaginous structure, creating a diagnostic gap in forensic investigations.

Objective: To explore the feasibility of micro-computed tomography (micro-CT) and diffusible iodine-based contrast-enhanced computed tomography (diceCT) as high-resolution imaging techniques for detailed forensic and developmental assessment of the pediatric hyoid-larynx complex.

Materials And Methods: Five pediatric hyoid-larynx complex samples were obtained during forensic autopsies.

The value of micro-CT imaging in the forensic evaluation of neck trauma.

Aim: Forensic examination of the hyoid-larynx complex (HLC) is crucial in diagnosing (inflicted) neck trauma. Clinical Total-Body CT (TBCT) scans of the (non-)calcified HLC lack sensitivity for fracture detection. Micro-computed tomography (micro-CT) is an upcoming imaging modality capable of scanning samples at microscale resolution up to 1 µm.

Familial multiple discoid fibromas is linked to a locus on chromosome 5 including the FNIP1 gene.

Previously, we reported a series of families presenting with trichodiscomas, inherited in an autosomal dominant pattern. The phenotype was named familial multiple discoid fibromas (FMDF). The genetic cause of FMDF remained unknown so far.