Recognition of the HLA-C*05:37 Allele in a Taiwanese Individual.

One nucleotide substitution in codon 186 of HLA-C*05:01:01:01 results in a novel allele, HLA-C*05:37.

Detection of the HLA-B*54:21 Allele, a Variant of B*54:01:01:01, in a Taiwanese Individual.

One nucleotide mutation in exon 2 of HLA-B*54:01:01:01 results in the novel allele, HLA-B*54:21.

Detection of the HLA-B*15:88 Allele in a Taiwanese Individual.

Two nucleotide substitutions in codon 152 of HLA-B*15:02:01:01 result in a novel allele, HLA-B*15:88.

Detection of the HLA-A*02:924 Allele, a Variant of A*02:07:01:01, in a Taiwanese Individual.

One nucleotide mutation in exon 4 of HLA-A*02:07:01:01 results in the novel allele, HLA-A*02:924.

Detection of the HLA-B*27:247 Allele in Two Taiwanese Siblings.

One nucleotide substitution in codon -1 of HLA-B*27:04:01 results in a novel allele, HLA-B*27:247.

Identification of the HLA-DQB1*06:02:49 Allele in a Taiwanese Individual.

One nucleotide substitution at nucleotide 36 of HLA-DQB1*06:02:01:01 results in a novel allele HLA-DQB1*06:02:49.

Recognition of the HLA-C*03:86 Allele in a Taiwanese Individual.

Recombination between C*03:03:01:01 and C*01:02:01:01 results in the novel allele, HLA-C*03:86.

Recognition of the HLA-A*11:01:79 Allele in a Taiwanese Individual.

One nucleotide substitution in codon 335 of HLA-A*11:01:01:01 results in the novel allele HLA-A*11:01:79.

Discovery of the Novel HLA-B*58:01:50 Allele in a Taiwanese Individual.

Nucleotide substitution in codon 164 of HLA-B*58:01:01:01 results in the novel allele, HLA-B*58:01:50.

Recognition of HLA-DPB1 alleles and their associated HLA haplotypes in 55 randomized unrelated Taiwanese individuals.

Objectives: Here, we report the distribution of HLA-DPB1 alleles studied in a cohort of 55 randomly collected blood samples from unrelated Taiwanese individuals and the deduced most likely HLA haplotypes associated with the defined DPB1 alleles in the cohort. Our aim is to reveal the unprecedented data on the distribution of HLA-DPB1 alleles in the Taiwanese population and to find out the most probable HLA haplotypes associated with the HLA-DPB1 alleles detected.

Materials And Methods: The material for this study was blood samples, preserved in KEDTA and/or acid citrate dextrose anticoagulants.

Detection of the HLA-B*40:78 allele in a Taiwanese individual.

One nucleotide substitution in codon 136 of HLA-B*40:02:01:01 results in a novel allele, HLA-B*40:78.

Detection of the HLA-B*51:01:44 allele in a Taiwanese individual.

Nucleotide substitution in codon 221 of HLA-B*51:01:01:01 results in a novel allele, HLA-B*51:01:44.

Recognition of the HLA-B*40:400 allele and its associated HLA haplotype in a Taiwanese individual.

One nucleotide substitution in codon 81 of HLA-B*40:01:01 results in a novel allele, HLA-B*40:400.

Detection of the HLA-A*11:127N allele in a Taiwanese individual.

A nucleotide mutation in codon 171 of HLA-A*11:01:01:01 results in a novel allele HLA-A*11:127N.

Discovery of a novel HLA-A*11 null allele, HLA-A*11:466N, in a Taiwanese individual.

A nucleotide deletion in the residue 371 of HLA-A*11:01:01:01 results in a novel allele HLA-A*11:466N.

Detection of the HLA-C*08:66 allele in a Taiwanese individual.

Two nucleotide substitutions in codon 152 of HLA-C*08:01:01:01 result in a novel allele HLA-C*08:66.

Recognition of the HLA-DQB1*03:96 allele in a Taiwanese individual.

One nucleotide substitution in codon 130 of HLA-DQB1*03:03:02:01 results in a novel allele HLA-DQB1*03:96.

Discovery of the novel HLA-C*12:02:53 allele in a Taiwanese individual.

Nucleotide substitution in codon 238 of HLA-C*12:02:02:01 results in a novel allele, HLA-C*12:02:53.

Association of HLA-C*07:359 with HLA-A, -B, and -DRB1 alleles in Taiwanese.

Objectives: It is thought that Taiwanese indigenous people were the "first people" to populate Taiwan (Formosa) having been there for over 5000 years, preceding the Dutch colonization (from 1624 to 1662) and Spanish colonization (from 1626 to 1642). Taiwan's indigenes, represented by Austronesian language speakers, currently constitute approximately 2% of the total population in Taiwan. It is unknown whether they evolved from Taiwan's Paleolithic or Neolithic cultures, arrived during or after the Neolithic period from China or Southeast Asia or both.

Recognition of the HLA-C*07:359 allele in Taiwanese individuals.

One nucleotide substitution in codon 264 of HLA-C*07:02:01:01 results in a novel allele, HLA-C*07:359.

Detection of the HLA-B*40:01:35 allele in a Taiwanese individual.

Nucleotide substitutions in codons -1 and 84 of HLA-B*40:01:01 result in a novel allele, HLA-B*40:01:35.

Recognition of the HLA-A*02:840 allele, a variant of A*02:07:01:01, in a Taiwanese individual.

Two nucleotide substitutions in exon 3 of HLA-A*02:07:01:01 result in the novel allele, HLA-A*02:840.