Publications by authors named "Punithavathy Manickavasagam"
This study aimed at exploring microalgal heterogeneity from fresh water samples collected from inland water bodies in the heavily built city of Singapore. Culturable pure isolates (n = 94) were subject to an in-house microalgal DNA extraction method and LSU rDNA sequencing. Isolates were analysed for their predominance and distribution.
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- Researchers aimed to understand why oral vaccines, like the oral poliovirus vaccine (OPV), are less effective in low-income countries by analyzing immune responses in 292 infants from India.
- Despite measuring various immune factors, no specific immune profile was linked to the effectiveness of OPV, though higher stool viral pathogen presence was noted in infants who didn't respond to the vaccine.
- By using machine learning, they demonstrated that it's possible to predict vaccine response based on immune markers and infection status, achieving an accuracy of around 58%, but emphasized that better results may come from studying mucosal tissue more closely.
Diarrheal disease due to Group A rotaviruses remain a leading cause of mortality and morbidity in the less developed parts of the world. India has started a phased roll out of rotavirus vaccine in the national immunization program. This analysis summarizes the rotavirus genotype strain distribution pre-vaccine introduction in Vellore, India from December 2005 to June 2016.
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