Acute Posterior Multifocal Placoid Pigment Epitheliopathy-Like Panuveitis Following Mpox Vaccination.

Purpose: To report a case of APMPPE-like panuveitis following mpox vaccination.

Methods: Case report.

Results: A 37-year-old Chinese man presented with bilateral anterior and intermediate uveitis, retinal vasculitis and unilateral acute posterior multifocal placoid pigment epitheliopathy (APMPPE) 2 weeks following JYNNEOS mpox vaccination.

From Dysbiosis to Disease: The Microbiome's Influence on Uveitis Pathogenesis.

The microbiome, comprising the diverse microbial communities inhabiting the human body, has emerged as a critical factor in regulating immune function and inflammation. The relationship between the microbiome and uveitis represents a promising frontier in ophthalmological research, with the microbiome increasingly implicated in disease onset and progression. Research has predominantly focused on the gut microbiome, with animal studies providing evidence that dysbiosis is a key factor in autoimmunity.

Seasonal Variation in HLA-B27 Associated Uveitis.

Background: To examine if there was a monthly variation in HLA-B27-associated uveitis.

Methods: Retrospective review of all individuals presenting to a single centre with HLA-B27-associated uveitis from 2009 to 2020.

Results: 577 participants with HLA-B27-associated uveitis were included.

Uveitis and Scleritis as a Risk Factor for Mortality.

Purpose: Uveitis and scleritis may be caused by local or systemic infection, or associated with noninfectious systemic inflammatory autoimmune disease. This study explored the all-cause mortality following an individual's first presentation with uveitis/scleritis.

Methods: A cross-sectional study was conducted on all uveitis/scleritis patients diagnosed by uveitis specialists and treated in a single tertiary referral center in New Zealand between 2006 and 2020(15y).

Insights into the diagnosis and management of sarcoid uveitis: A review.

Sarcoidosis is a leading cause of non-infectious uveitis that commonly affects middle-aged individuals and has a female preponderance. The disease demonstrates age, sex and ethnic differences in clinical manifestations. A diagnosis of sarcoidosis is made based on a compatible clinical presentation, supporting investigations and histologic evidence of non-caseating granulomas, although biopsy is not always possible.

The spectrum of paediatric uveitis in New Zealand.

Aims: To describe the aetiology, complications, treatment and outcomes of paediatric uveitis.

Methods: This was a retrospective chart review including all paediatric participants presenting with uveitis to a tertiary referral hospital in Auckland, New Zealand between January 1997 and March 2020.

Results: Two hundred and twenty-four eyes of 143 participants were included.

Long term outcome and prognostic indicators in Posner Schlossman syndrome.

Background: Posner Schlossman syndrome is a well-defined uveitis entity that is characterised by relapsing remitting unilateral anterior uveitis with markedly raised intraocular pressure. The aim of this study was to determine the risk factors for progression in patients with Posner Schlossman syndrome.

Methods: Ninety-eight patients were enrolled in a retrospective case series.

Acute posterior multifocal placoid pigment epitheliopathy: clinical presentation and risk of stroke and transient ischaemic attack.

Background/aims: Acute posterior multifocal placoid pigment epitheliopathy is a rare but important disease that can be associated with life-threatening complications due to cerebral vasculitis. The primary objective was to determine the incidence of neurological complications and risk factors for stroke and transient ischaemic attack (TIA) associated with acute posterior multifocal placoid pigment epitheliopathy. Secondary objectives included the clinical presentation, visual outcomes and recurrence rates.

Endogenous Endophthalmitis: A 21-Year Review of Cases at a Tertiary Eye Care Centre.

Purpose: Endogenous endophthalmitis is rare and associated with significant morbidity and mortality. The primary objective was to identify causative organisms. Secondary objectives included the determination of systemic risk factors and visual prognostic factors.