Publications by authors named "Pravinkumar Kandhare"
Article Synopsis
- The International Cardiac Arrest Research (I-CARE) aims to create a standardized database for studying acute brain injury in cardiac arrest patients through continuous electroencephalography (EEG) across multiple centers in the US and Europe.
- Data from 1,020 comatose patients were collected, including 56,676 hours of EEG monitoring, revealing that most patients did not survive, while some achieved varying degrees of neurological recovery.
- The database highlights significant findings, like variations in EEG patterns based on neurological outcomes, and includes features like spike frequency and burst suppression, which have implications for understanding brain function after cardiac arrest.
Objective: To develop a harmonized multicenter clinical and electroencephalography (EEG) database for acute hypoxic-ischemic brain injury research involving patients with cardiac arrest.
Design: Multicenter cohort, partly prospective and partly retrospective.
Setting: Seven academic or teaching hospitals from the U.
Prior Treatment Time Affects Survival Outcomes in Metastatic Breast Cancer.
JCO Clin Cancer Inform
June 2020
Purpose: Sequential drug treatments in metastatic breast cancer (MBC) are disparate. Clinical trial data includes limited reporting of treatment context, primarily including the number of prior therapies. This study evaluates the relationship between prior treatment time, prior lines of treatment, and survival using a novel visualization technique coupled with statistical analyses.
View Article and Find Full Text PDFVisualization of Sequential Treatments in Metastatic Breast Cancer.
JCO Clin Cancer Inform
March 2019
Purpose: Treatment sequencing of metastatic breast cancer (MBC) is heterogeneous. The primary objective of this study was to develop a visualization technique to understand population-level treatment sequencing for MBC. Secondary outcomes were to describe the heterogeneity of MBC treatment sequencing, as measured by the proportion of patients with a rare sequence, and to generate hypotheses about the impact of sequencing on overall survival.
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