Publications by authors named "Pravinkumar Choudhary"
Glycosylated bacteriocins, known as glycocins, were first discovered in 2011. These bioactive peptides are produced by bacteria to gain survival advantages. They exhibit diverse types of glycans and demonstrate varied antimicrobial activity.
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- Glycosylated bacteriocins, also known as glycocins, show promise as natural food preservatives and alternatives to antibiotics, but researchers need effective methods for their laboratory evolution.
- A new high-throughput screening method called SELECT-GLYCOCIN was developed, which utilizes an enzyme from Enterococcus faecalis to create and test libraries of modified glycocins against food-borne pathogens.
- Through this method, a diverse range of mutant glycocins was generated and screened, leading to the identification of several potential antimicrobial variants that could be useful in food preservation and drug development.
O-GlcNAcylation is an important post-translational modification of proteins. O-GlcNAcylated proteins have crucial roles in several cellular contexts both in eukaryotes and bacteria. O-GlcNActransferase (OGT) is the enzyme instrumental in O-GlcNAcylation of proteins.
View Article and Find Full Text PDFKnowledge of glycosylation status and glycan-pattern of proteins are of considerable medical, academic and application interest. ProGlycProt V2.0 (www.
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