Publications by authors named "Pascal Rosamel"

Background: Surgical rib fixation for multiple rib fractures and flail chest has become more common in the 2000s with interesting results in selected patients. However, surgical rib fixation lacks a consensus on the delay to surgery and the benefits on postoperative clinical outcomes. Our goal was to determine if delay to surgery can affect postoperative outcomes.

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Article Synopsis
  • A study on Stage IVa thymoma, a rare cancer, evaluated the effects of subtotal pleurectomy and HITHOC treatment on patients with either de novo tumors or distant relapses.
  • The research analyzed 40 patients over 24 years, finding a hospital mortality rate of 2.5% and significant differences in disease-free intervals between de novo tumors (49 months) and distant relapses (85 months).
  • The study concludes that HITHOC combined with pleurectomy may yield favorable outcomes for selected patients, but more multicentric research is necessary to establish it as a standard treatment.
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Several surgical procedures, from debulking to extrapleural pneumonectomy, may be applied for stage IVa Masaoka thymomas, but their efficiency is still controversial. Case studies have favored R resection as the cornerstone of multimodal therapy for locoregional metastatic extension. This report describes a standardized procedure combining a cytoreductive surgical procedure and intrathoracic chemohyperthermia on a 46-year-old patient presenting with B2 thymoma and synchronous unilateral pleural metastasis.

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Objective: To evaluate the ability of the third-generation (3.01) of FloTrac/Vigileo monitor (Edwards Lifesciences, Irvine, CA) to follow variations in cardiac output (∆CO) using the new polar plot approach.

Design: Prospective interventional study.

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Objectives: Tissue oxygen saturation (StO(2)) assessed using Near Infrared Spectroscopy and its derived parameters during a vascular occlusion test (VOT) can detect microvascular changes in septic shock patients. General anesthesia (GA) impacts microcirculation. Our aim was to study the effects of general anesthesia on StO(2) and StO(2) derived parameters obtained during VOT in patients referred for cardiac surgery.

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Background: Respiratory variations in the pulse oximeter plethysmographic waveform amplitude (deltaPOP) are sensitive to changes in preload and can predict fluid responsiveness in mechanically ventilated patients. However, they cannot be easily calculated from a bedside monitor. Pleth variability index (PVI, Masimo Corp.

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Article Synopsis
  • DeltaPOP is a measure of respiratory variations in pulse oximetry waveform amplitude, and it can indicate fluid responsiveness in patients on mechanical ventilation during anesthesia.
  • A study involving 25 cardiac surgery patients showed that changes in DeltaPOP and DeltaPP (another hemodynamic measurement) were significantly greater in patients who responded positively to volume expansion (fluid infusion).
  • The research found that a DeltaPOP greater than 13% before fluid administration accurately identified responders with high sensitivity (80%) and specificity (90%), suggesting its potential for clinical use in monitoring fluid responsiveness.
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Cardiac resynchronization therapy improves symptoms and survival in chronic heart failure patients, but has been poorly studied in the acute heart failure setting. We report the case of successful cardiac resynchronization therapy in the early postoperative period after cardiac surgery in a patient with left bundle branch block and proven ventricular dyssynchrony.

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Aortic valvular surgery is often challenging in patients with coronary artery bypass (CABG) using in situ right internal thoracic artery (RITA) crossing in front of the aorta to the left anterior descending artery (LAD). Full sternotomy and aortic dissection result sometimes in graft injury and subsequent myocardial ischemia. The benefit of an inferior T hemisternotomy through the second intercostal space is discussed.

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Objective: Many changes have occurred in the natural history and the management of active infectious endocarditis (AIE) in recent years. Therefore, the records of patients admitted in a tertiary care specialized hospital presenting with the Duke criteria were reviewed.

Methods: Adults operated on to treat AIE were included during a 3-year period.

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