Publications by authors named "Pascal Mputu Mputu"
Using midodrine to accelerate weaning of intravenous vasopressors in acute spinal cord injured patients admitted to the intensive care unit: A retrospective study of 28 patients.
J Spinal Cord Med
September 2025
Study Design: A retrospective study with a crossover design.
Objectives: Maintaining mean arterial pressure (MAP) is crucial in the early management of SCI, yet the role of oral midodrine in this setting remains unclear. This study evaluates whether midodrine facilitates IV vasopressor weaning within 24 hours of initiation.
Article Synopsis
- The study aims to categorize patient subgroups post-spinal cord injury (SCI) based on their functional recovery, using specific clinical assessment tools.
- The analysis included data from 675 patients in the Rick-Hansen Registry and identified four distinct subgroups with varying functional outcomes measured by the Spinal Cord Independence Measure (SCIM).
- Findings indicated that improved sensory function, particularly a pinprick score of 27 or higher, is associated with better motor recovery, suggesting its significance in rehabilitation planning for clinicians.
Does Improvement in American Spinal Injury Association Impairment Scale Grade Correlate With Functional Recovery in All Patients With a Traumatic Spinal Cord Injury?
Am J Phys Med Rehabil
February 2024
Objective: The aim of the study is to determine what improvement on the American Spinal Injury Impairment Scale correlates with functional status after a traumatic spinal cord injury.
Design: We performed an observational cohort study, analyzing prospective data from 168 patients with traumatic spinal cord injury admitted to a single level 1 trauma center. A multivariable analysis was performed to assess the relationship between functional status (from the Spinal Cord Independence Measure) at 1-year follow-up and American Spinal Injury Impairment Scale grade (baseline and 1-yr follow-up), while taking into account covariables describing the sociodemographic status, trauma severity, and level of neurological injury.
Article Synopsis
- The study examines eligibility criteria for discharging individuals with traumatic spinal cord injury (AIS-D) to home-based rehabilitation instead of inpatient facilities, aiming to enhance resource utilization.
- About 37.9% of participants met the criteria for home rehabilitation, showing younger age and better overall health compared to those who went to inpatient care.
- The results indicate that home-based rehabilitation leads to better long-term functional status and quality of life without causing any readmissions due to rehabilitation failures.
Background: Neurological outcomes after traumatic spinal cord injury are variable and depend on patient-, trauma-, and treatment-related factors as well as on spinal cord injury characteristics, imaging, and biomarkers.
Objective: The aims of the study were to identify and classify the early predictors of neurological outcomes after traumatic spinal cord injury.
Data Sources: The Medline, PubMed, Embase, and the Cochrane Central Database were searched using medical subject headings.