Uveitis in Parry-Romberg syndrome: A case report and review of literature.

Parry-Romberg syndrome (PRS) is a rare, acquired condition characterized by progressive atrophy of the skin and soft tissue of one side. A 35-year-old female with a 4-year history of recurrent uveitis and hypotony in the right eye, previously diagnosed with granulomatous anterior uveitis and pars planitis, was referred to our clinic. Despite treatment, she continued to develop recurrences of inflammation, with intraocular pressure dropping to 0 mmHg twice.

Tuberculous endogenous endophthalmitis presenting acute anterior uveitis with hypopyon.

A 27-year-old male with pain, redness, and vision loss in the right eye was diagnosed with acute anterior uveitis with hypopyon and treated with topical corticosteroid and cycloplegic eyedrops. Two weeks later, he developed severe vitritis. Then, after 1 month of oral corticosteroid treatment, his condition did not improve; therefore, he underwent pars plana vitrectomy with intravitreal antimicrobial injection in the right eye with suspicion of endogenous endophthalmitis.

JAK-STAT inhibitors in noninfectious uveitis - A review.

The management of noninfectious uveitis (NIU) has involved the use of corticosteroids and immunomodulators (IMT). However, a certain subset of NIU patients does not respond to conventional IMT therapy, such as methotrexate and azathioprine. In these patients, biological IMT with specific targets is employed.

Bilateral Neuroretinitis Following Treatment with Sofosbuvir and Velpatasvir.

Purpose: We report a case of bilateral neuroretinitis like picture following ingestion of Direct Acting Antivirals (DAAs) in the form of sofosbuvir and velpatasvir, for treatment of Chronic Hepatitis C infection.

Methods: retrospective observational case report and review of literature.

Results: A healthy 49 years old male, known case of Chronic heptatis C; developed bilateral painless diminution of vision following treatment with DAAs-sofosbuvir and velpatasvir-for treatment-naïve hepatitis C.

An Unusual Case of Exudative Retinal Detachment in a 6-Year-Old Child with Acute Retinal Necrosis.

Purpose: To report a case of exudative retinal detachment (ERD) in a child with Acute retinal necrosis (ARN).

Method: Retrospective Chart Review.

Result: A six-year-old boy presented with anterior uveitis with hypopyon and exudative retinal detachment with peripheral confluent patches of retinitis in the left eye.

Indocyanine green angiography reveals choroidal hypoperfusion in subacute sclerosing panencephalitis (SSPE).

We report the choroidal findings on indocyanine green angiography (ICGA) in two cases of subacute sclerosing panencephalitis (SSPE). The two immunocompetent patients (31-year-old and 30-year-old Asian Indian males) presented with acute-onset rapidly progressing vision loss with findings of necrotizing retinitis involving the central macula. Both patients tested negative for serological evidence of herpes or varicella, and toxoplasma antibodies.

Clinical Profile and Ocular Morbidities in Patients with Both Diabetic Retinopathy and Uveitis.

Purpose: To describe the clinical profile and complications of diabetic retinopathy (DR) and uveitis in patients with coexisting conditions and to derive associations based on site of primary inflammation, stage of DR, and complications of each.

Design: Single-center, cross-sectional observational study.

Participants: Sixty-six patients with coexisting DR and uveitis.

Paenibacillus lautus: A new foe in endogenous endophthalmitis.

Purpose: To discuss the diagnosis and management of a rare case of endogenous endophthalmitis (EE) caused by Paenibacillus lautus mimicking granulomatous uveitis in a child, highlighting the use of 16S rRNA gene amplicon sequencing as an accurate method to identify rare pathogens.

Method: A retrospective chart review of the clinical presentation, microbiologic workup-including microscopy, culture, antibiotic susceptibility, and polymerase chain reaction for pathogen DNA of clinical samples-and the clinical management of the case were recorded.

Result: A 13-year-old boy presented with decreased vision in the right eye for one month.

Surgically induced necrotizing scleritis (SINS): Is it a standalone condition or a variant of necrotizing scleritis?

Purpose: To report the clinical pattern of surgically induced necrotizing scleritis (SINS) in a tertiary eye care center in Southern India.

Methods: Retrospective analysis of all SINS cases visiting the uveitis clinic of a tertiary eye institute between January 2009 and April 2019.

Results: In total, 15 patients with a median age of 65 (IQR: 52-70) years were included in the study.

Masquerade syndrome: A review of uveitic imposters.

Masquerade syndromes in uveitis are complex clinical conditions where non-inflammatory diseases mimic uveitic manifestations, often leading to diagnostic and therapeutic challenges. This review delves into the diverse spectrum of masquerade syndromes, categorizing them into neoplastic and non-neoplastic entities. We explore the prevalence of primary intraocular lymphoma, leukaemia, retinoblastoma, and other malignancies, as well as conditions like retinitis pigmentosa and endophthalmitis that can present as uveitis.

A case of granulomatosis with polyangiitis-associated scleritis presenting as conjunctivitis.

A 42-year-old male presented initially with conjunctivitis and was treated with topical medical medications without any improvement. He developed ocular pain subsequently and further examination revealed lid edema, conjunctival hyperemia with chemosis, matting of lashes with yellowish discharge, and deeper episcleral congestion which did not blanch with topical vasoconstrictor. Subsequent laboratory investigation revealed positive cytoplasmic-antineutrophil cytoplasmic antibody (Anti-PR 3 antibody).

An Analysis of the clinical and investigative profile of uveitis in the elderly: First case series from India.

Purpose: To evaluate the spectrum of uveitis occurring after 60 years of age in elderly patients who presented to a tertiary care eye center in India.

Methods: Retrospective study of patients who visited a tertiary eye care institute between January 2010 and July 2020.

Result: Eighty-seven patients developed uveitis after 60 years, with only 44.

Current understanding of acute zonal occult outer retinopathy (AZOOR).

Acute Zonal Occult Outer Retinopathy (AZOOR) is characterized by sudden visual impairment, often presenting with scotoma and photopsia in young to middle-aged adults, showing a female predominance. This condition, distinct from genetic disorders like retinitis pigmentosa, lacks a hereditary basis and exhibits unique fundus changes and imaging features indicative of outer retinal dysfunction. Recent advancements have broadened our understanding, identifying variants like Acute Annular Outer Retinopathy (AAOR) and Multizonal outer retinopathy and retinal pigment epitheliopathy (MORR), each with specific clinical presentations and imaging characteristics.

Retinal Vasoproliferative Tumours in Uveitis.

Purpose: To describe a cohort of patients with retinal vasoproliferative tumours (RVPT) seen in the uveitis clinic of a single tertiary eye care institute in India.

Methods: Retrospective Chart Review.

Results: In our study of 17 patients with 18 eyes affected by RVPTs, 94.

A COVID-19 perspective of multiple evanescent white dot syndrome (MEWDS).

Multiple evanescent white dot syndrome (MEWDS) is a rare form of posterior uveitis characterized by involvement in the posterior pole and mid-periphery. A viral etiology that provokes an immune-mediated response has been hypothesized to be the inciting factor of the pathology. Recently, there has been an increase in the literature regarding new-onset uveitis and reactivation of previously diagnosed cases of uveitis following COVID-19 vaccinations.

Retinal Vasculitis in a Patient with Rhupus.

This case report describes a case of retinal vasculitis in a patient with Rhupus, which has not been reported earlier in the literature. A 39-year-old female patient with a history of Rhupus presented with sudden vision loss in her left eye. The patient was treated earlier, for her polyarthritis, with oral corticosteroids, hydroxychloroquine, and oral methotrexate, which were discontinued after 1 year of treatment.