Cellular apoptosis: An alternative mechanism of action for caspofungin against .

Background And Purpose: Although the mechanism of action for echinocandins is known, the physiological mechanisms by which these antifungal agents cause cell death via the classical apoptotic pathways are not well-defined yet. Regarding this, the present study aimed to evaluate the mechanisms of caspofungin-induced cell death.

Materials And Methods: For the purpose of the study, the minimum inhibitory concentration (MIC) of caspofungin against (ATCC 90030) was determined using the broth microdilution reference method (CLSI M27-A2 and M27-S4).