Publications by authors named "Pablo de Matos Monteiro"
Ellagic Acid Potentiates the Inhibitory Effects of Fluconazole Against .
Antibiotics (Basel)
December 2024
: Antifungal resistance to azoles, coupled with the increasing prevalence of infections, represents a significant public health challenge and has driven the search for new natural compounds that can act as alternatives or adjuvants to the current antifungals. Ellagic acid (EA) has demonstrated antifungal activity; however, its effects are not fully understood. In this study, we investigated the in vitro anti- activity of EA and its ability to potentiate the effects of fluconazole (FLZ) on : The Minimum Inhibitory Concentration (MIC) of EA was determined by broth microdilution and its interaction with FLZ was assessed using a checkerboard assay.
View Article and Find Full Text PDFHuman papillomavirus in women infected with human immunodeficiency virus: association with viral load and lymphocyte count.
Rev Inst Med Trop Sao Paulo
June 2024
Article Synopsis
- * The study involved 86 HIV-positive women, analyzing samples from cervical, anal, and oral areas to check for the presence of HPV and its types in relation to their health data, including viral load and T cell counts.
- * Results showed a significant prevalence of HPV, especially in cervical (65.9%) and anal (63.8%) mucosa, with a viral load of ≥75 HIV copies/mL being linked to the presence of HPV-DNA.
Background: A high prevalence and incidence of head and neck tumors make Brazil the country with the third-highest number of cases of these malignant neoplasms. The main risk factors are smoking and alcohol consumption; however, cases related to the human papillomavirus (HPV) have tripled in number, demonstrating a changing disease profile. Studies have reported the prevalence of HPV in laryngeal squamous cell carcinoma (LSCC) to vary between 8% and 83%.
View Article and Find Full Text PDFArticle Synopsis
- This study analyzed 25 cases of recurrent respiratory papillomatosis (RRP) in Brazil, focusing on patient demographics, clinical features, and HPV infection status over an 11-year period.
- The majority of patients were young (median age 12.4 years), with juvenile RRP being more common (68%), and the most frequent symptom was dysphonia; 56% experienced recurrences, while tracheostomy was required for 26.9%.
- HPV-6 was the most prevalent type among the patients, with a significant portion infected with low-risk and high-risk HPV strains, suggesting a need for further research to understand the disease and its implications better.
and Its Association with Other Sexually Transmitted Coinfection among Sexually Active Women from the Northeast of Brazil.
Interdiscip Perspect Infect Dis
October 2020
Objective: To verify the association between HPV infection and the presence of coinfections (, , and ) in women in the state of Maranhão.
Methods: HPV-DNA detection was performed by the nested PCR, using the primers PGMY09/11 and GP + 5/GP + 6. For the identification of sexually transmitted agents, conventional PCR was performed using the following primers: KL1/KL2 (), TVA5/TVA6 (), and HO1/HO3 ().