Publications by authors named "Nurit Nachum"
Elderly-Onset Inflammatory Bowel Disease Has Distinct Disease Characteristics and Treatment Patterns.
United European Gastroenterol J
August 2025
Background And Aims: Elderly-onset inflammatory bowel disease (IBD) patients (age ≥ 60 at diagnosis) have unique characteristics that require special consideration. Using a real-life registry-based cohort, we compared disease phenotypes and treatment exposures between adult-onset (18 ≤ age < 60 years) and elderly-onset IBD patients.
Methods: Demographics, disease characteristics, and treatment were compared between adult- and elderly-onset IBD patients diagnosed during 2000-2022 with ≥ 12 months follow-up.
Article Synopsis
- Curcumin and Qing Dai (QD) are herbal treatments found effective for ulcerative colitis (UC) in children, used since 2016 in a combination called CurQD.
- A study involving 30 pediatric patients showed significant improvements, with over 50% experiencing a substantial reduction in disease activity and fecal calprotectin levels during treatment.
- Follow-up results indicated that while 33% experienced a flare-up, many regained remission or responded well to adjustments in their treatment regimen, suggesting CurQD is both effective and safe for managing mild to moderate UC.
Clinical characteristics and outcomes of pediatric patients with autoimmune gastritis.
Maya Granot
,
Beate C Beinvogl
,
Michael Schvimer
,
Jeffrey D Goldsmith
,
Manar Matar
,
Nurit Nachum
J Pediatr Gastroenterol Nutr
September 2024
Article Synopsis
- Autoimmune gastritis (AIG) is a rare and chronic inflammatory disorder in children, which can lead to long-term complications like gastric cancer, but little is known about its natural progression in pediatric cases.
- A study tracked 33 children diagnosed with AIG over a period of more than two decades, finding that a significant number (66.7%) had specific antibodies and that iron deficiency anemia was the most common symptom (75%).
- The study emphasizes the need for monitoring due to high rates of metaplasia (33% in follow-ups) and a reported case of a type 1 gastric neuroendocrine tumor, indicating that AIG needs careful surveillance even in the absence of H. pylori infection.