Impact of xylene exposure during organogenesis on foeto-placental efficiency and foetal viability: Exploring its association with oxidative stress-induced inflammation and apoptosis .

The potential maternal and foetal toxicity resulting from exposure to xylene at or below the allowable limit of 100 ppm during gestation is not thoroughly studied. The aim of this study was to investigate maternal and foetal outcomes following prenatal exposure to xylene during organogenesis. Pregnant Sprague Dawley (SD) rats were administered intraperitoneal (IP) corn oil (vehicle), 100, 500, and 1000 parts per million (ppm) of xylene from gestational day (GD) 6 until GD17.

Toxicological Effects of Technical Xylene Mixtures on the Female Reproductive System: A Systematic Review.

Technical xylene is a compound of massive production that is used in applications such as petrochemical and healthcare laboratories. Exposure to xylene can cause acute and chronic effects in humans and animals. Currently available studies regarding xylene's adverse effects with credible designs were dated almost twenty years ago.