Publications by authors named "Nishi Modi"
The human gut flora of trillions of bacteria is vital for general health and greatly influences digestion, immune system function, and brain development. Through neuronal, hormonal, and immunological channels, the gut-brain axis (GBA), a bidirectional communication network, links the gut microbiota to the central nervous system (CNS). This relationship has been linked to affective diseases, including depression and anxiety, as well as mental health issues.
View Article and Find Full Text PDFIntroduction: Alzheimer's disease can cause dementia through brain matter degradation. This study investigates the monoclonal antibody usage for AD treatment, following PRISMA 2020 guidelines, and aims to discern the monoclonal antibody that offers the optimal balance of efficacy and safety for individuals with AD.
Methods: A systematic search was conducted across databases such as PubMed, Cochrane Library, and clinical trial registries for randomized controlled trials.
Article Synopsis
- * Brexanolone and zuranolone are particularly effective for postpartum depression, providing rapid symptom relief through their action on the GABA system, as shown in clinical trials.
- * Beyond mood disorders, ganaxalone shows promise for managing epilepsy by controlling seizures via GABAergic activity, and neurosteroids may offer neuroprotection in Alzheimer's models, suggesting their potential to mitigate excitotoxicity and slow neurodegeneration.
Organophosphate Compound Poisoning - An Unusual Presentation as Guillain Barre Syndrome.
Ann Indian Acad Neurol
October 2023
The COVID-19 outbreak has emerged as one of the most profound medical events of the 21st century, leaving an indelible impact on a global scale. The widespread prevalence causing significant illness and death needs collaborative and inventive efforts to deal with this challenge. One of the particular subset of the general population that had endured a significant impact was the pregnant population.
View Article and Find Full Text PDFIntroduction Somatoform disorders (SFDs) are a spectrum of diseases mainly manifesting with physical symptoms of no recognizable etiology. These disorders are believed to be primarily influenced and exacerbated by psychological factors. Given the connection between parental sociodemographics and psychological factors and SFDs, there is a pressing need to investigate this area further, particularly concerning parents and their children affected by somatoform disorders.
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