Identifying general surgery trainees' perception of leadership, leadership needs, and development of a leadership curriculum.

Objective: Leadership is an essential competency for surgeons. Despite its importance, leadership is not explicitly taught in many residency programs. The objective of this study was to explore general surgery residents' perceptions of leadership, its domains and competencies, and the need for and structure of its development in residency.

Global Prevalence of Metabolic Syndrome in Schizophrenia Patients: A Systematic Review and Meta-Analysis.

The prevalence of metabolic syndrome in patients with schizophrenia has significantly increased and can be associated with severe complications such as chronic diseases and mortality. Despite numerous studies, a comprehensive estimate of the prevalence of metabolic syndrome in schizophrenia patients is lacking. Therefore, this study aimed to estimate the global prevalence of metabolic syndrome in schizophrenia patients through a systematic review and meta-analysis.

Impact of Covid-19 pandemic on volume and surgeon professional fees generated by emergency general surgery procedures.

Introduction: The COVID-19 pandemic has changed the dynamics of healthcare in the USA. In early 2020, most states issued orders to stop non-emergent elective surgeries. This contracted the overall revenue generated by the hospital systems.

Septic arthritis of the hip, an unreported complication of perforated appendicitis: A case report.

Introduction: Progression of inflammation in acute appendicitis can lead to appendiceal perforation, which is associated with higher morbidity and mortality. Bacteremia due to a perforated appendicitis can lead to distal bacterial seeding, resulting in further complications.

Presentation Of Case: We present here a case of appendiceal perforation in a 32-year-old previously healthy male.

Tolerance induction by hematopoietic cell transplantation: combined use of stem cells and progenitor cells.

Background: Donor-specific hematopoietic cell transplantation (HCT) in the form of bone marrow transplantation has been long recognized experimentally as a means of inducing tolerance for subsequently transplanted organs. Clinical translation has been limited, however, due to HCT-associated complications. Unrelated myeloid progenitors (MP) can be administered simultaneously with hematopoietic stem cells (HSC).

Critical structural motif for the catalytic inhibition of human topoisomerase II by UK-1 and analogs.

Three new analogs of UK-1 have been synthesized and their efficacies as topoisomerase II inhibitors have been determined. Results show that UK-1 and two of these analogs are catalytic inhibitors of topo II and identifies a critical structure motif necessary for enzyme inhibition.