These two cases involve two patients with intestinal tuberculosis and severe lower gastrointestinal (GI) bleeding. The first case was a young woman who lived with HIV/AIDS and disseminated tuberculosis with wasting, pulmonary, and abdominal involvement that, despite the usual tuberculostatic treatment, evolved with a massive GI bleed. Her colonoscopy showed granulomatous colitis with active bleeding, and her biopsy showed positive acid-fast bacilli, confirming the diagnosis.
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