Publications by authors named "Nguyen Vinh Trung"
Prevalence, antimicrobial resistance and genomic comparison of non-typhoidal salmonella isolated from pig farms with different levels of intensification in Yangon Region, Myanmar.
PLoS One
September 2024
Article Synopsis
- In Myanmar, different types of pig farming coexist, but there's a lack of understanding about the zoonotic risks and antimicrobial resistance (AMR) linked to these practices, prompting this study focused on Salmonella.
- The study found a significant prevalence of Salmonella across various pig farms, with backyard farms having the highest incidence, and intensive farms showing a concerning level of multi-drug resistant strains.
- The research highlighted the presence of various Salmonella serovars, especially in semi-intensive and backyard farms, indicating a need for future monitoring and risk management to address zoonotic concerns and AMR in pig farming.
Article Synopsis
- * A study of 14,850 human and 1,666 environmental metagenomes revealed that certain concerning AR genes, such as CTX-M and various carbapenemases, are mostly restricted to specific bacteria like Proteobacteria and Bacteroides.
- * Despite the ability of some AR genes to adapt between different bacterial groups, they have not widely spread within diverse gut microbiota, suggesting a limited transfer of clinically relevant resistance traits.
Background: Nontyphoidal Salmonella (NTS) are associated with both diarrhea and bacteremia. Antimicrobial resistance (AMR) is common in NTS in low-middle income countries, but the major source(s) of AMR NTS in humans are not known. Here, we aimed to assess the role of animals as a source of AMR in human NTS infections in Vietnam.
View Article and Find Full Text PDFObjectives: To investigate the risk of colonization with ESBL-producing Escherichia coli (ESBL-Ec) in humans in Vietnam associated with non-intensive chicken farming.
Methods: Faecal samples from 204 randomly selected farmers and their chickens, and from 306 age- and sex-matched community-based individuals who did not raise poultry were collected. Antimicrobial usage in chickens and humans was assessed by medicine cabinet surveys.
Nontyphoidal (NTS), particularly serovar Typhimurium, is among the leading etiologic agents of bacterial enterocolitis globally and a well-characterized cause of invasive disease (iNTS) in sub-Saharan Africa. In contrast, Typhimurium is poorly defined in Southeast Asia, a known hot spot for zoonotic disease with a recently described burden of iNTS disease. Here, we aimed to add insight into the epidemiology and potential impact of zoonotic transfer and antimicrobial resistance (AMR) in Typhimurium associated with iNTS and enterocolitis in Vietnam.
View Article and Find Full Text PDFWe investigated the consequences of colistin use in backyard chicken farms in Vietnam by examining the prevalence of mcr-1 in fecal samples from chickens and humans. Detection of mcr-1-carrying bacteria in chicken samples was associated with colistin use and detection in human samples with exposure to mcr-1-positive chickens.
View Article and Find Full Text PDFBackground: Enteroaggregative (EAEC) and Shiga-toxin producing Escherichia coli (STEC) are a major cause of diarrhea worldwide. E. coli carrying both virulence factors characteristic for EAEC and STEC and producing extended-spectrum beta-lactamase caused severe and protracted disease during an outbreak of E.
View Article and Find Full Text PDFAntimicrobials are extensively used as growth promoters in animal feeds worldwide, but reliable estimates are lacking. We conducted an internet-based survey of commercial chicken and pig feed products officially approved for sale in Vietnam over the period March-June 2015. Information on the antimicrobial contents in feed products, alongside animal production data, was used to estimate in-feed antimicrobial consumption to produce one kilogram of live animal (chicken, pig), as well as to estimate country-wide antimicrobial consumption through animal feeds.
View Article and Find Full Text PDFArticle Synopsis
- The study investigated how common antimicrobial resistance is among E. coli found on chicken farms in southern Vietnam, linking this resistance to specific farming practices and antibiotic use.
- Data was collected from 208 farms, with E. coli isolated and tested for resistance to 11 antimicrobials. Findings showed high levels of resistance, particularly to gentamicin and ciprofloxacin, and specific farming practices exacerbated this issue.
- The results indicated that frequent antibiotic use on these farms contributes to significant resistance rates, highlighting potential risks for both environmental and human health.