Anti-Leukemic Profiling of Oxazole-Linked Oxadiazole Derivatives: A Computational and Kinetic Approach.

Leukemia is a common cancer that arises in both children and adults when bone marrow's hematopoietic stem cells proliferate unrestrained because of anomalies in normal cell regulatory systems. The present study focused on biological evaluation of oxazole-based oxadiazole scaffolds to evaluate the anti-proliferative effect on leukemic cancer cell lines. All novel oxazole-based oxadiazole scaffolds were synthesized and structurally characterized via C NMR, H NMR, and HREI-MS.