A multi-site comparison of the multimodal response to an acute social stressor in the MRI environment.

Understanding the mechanisms behind (mal)adaptive stress responses is crucial for addressing stress-related mental disorders, which remain leading contributors to global disability and mortality. However, individual differences in stress responses present a challenge for single studies due to limited sample sizes. Multi-site studies can overcome this by increasing statistical power and generalizability, but it remains unclear whether even optimally harmonized procedures can ensure cross-site comparability.

Psychological Resilience Factors and Their Association With Weekly Stressor Reactivity During the COVID-19 Outbreak in Europe: Prospective Longitudinal Study.

Background: Cross-sectional relationships between psychosocial resilience factors (RFs) and resilience, operationalized as the outcome of low mental health reactivity to stressor exposure (low "stressor reactivity" [SR]), were reported during the first wave of the COVID-19 pandemic in 2020.

Objective: Extending these findings, we here examined prospective relationships and weekly dynamics between the same RFs and SR in a longitudinal sample during the aftermath of the first wave in several European countries.

Methods: Over 5 weeks of app-based assessments, participants reported weekly stressor exposure, mental health problems, RFs, and demographic data in 1 of 6 different languages.