Investigating the role of genetic variations of (rs1045642) and (rs3808607) genes on serum lipid level among Malaysian male patients treated with atorvastatin.

Objective: To explore the allele frequency and associations between the presence of single nucleotide polymorphisms (SNP) in the (rs1045642) and (rs3808607) genes on lipid-lowering efficacy of atorvastatin among Malaysian male patients.

Method: The study included 64 subjects from a previous genetic association study among male patients who were on atorvastatin. The study was carried out at HUSM, Kelantan, Malaysia from December 2023 to October 2024.