Role of Yoga in Distinctly Targeting Modifiable Risk Factors in Type 2 Diabetes to Improve Immuno-Metabolic Axis.

Modifiable and non-modifiable risk factors in Type 2 Diabetes (T2D) contribute to chronic inflammation characterized by elevated pro-inflammatory mediators and constitutively activated immune cells. Chronic inflammation in T2D leads to perturbations in metabolism, resulting in altered immuno-metabolic axis and further vascular complications. Hence, reducing inflammation by targeting modifiable risk factors such as adiposity, sedentary lifestyle and psychological stress in T2D may facilitate efficient clinical management.

Impact Of Spinal Flexion and Extension-Based Yoga Asanas on Autonomic Variables in Experienced Yogic Practitioners: Study Protocol for a Randomized Crossover Trial.

Background: The autonomic nervous system (ANS) is a complex network responsible for maintaining homeostasis. Yoga, as a traditional mind-body intervention, is known to modulate autonomic function in both healthy and clinical populations. However, the differential effects of forward versus backward-bending yoga asanas on autonomic parameters remain unexplored.

Gynaecological reirradiation with image-guided radiotherapy: Tumour Control Probability and Normal Tissue Complication Probability in pre-immunotherapy era.

Background And Purpose: Management of recurrent gynaecological cancers after previous pelvic radiation is challenging. This institutional cohort describes clinical outcomes with image-guided radiotherapy techniques.

Materials And Methods: From 2020 to 2023, patients with recurrent or second primary gynaecological malignancies previously treated with radiotherapy were included.

The mediating influence of serum Klotho levels and the KL-VS heterozygosity on telomere shortening in schizophrenia.

Schizophrenia (SZ) has a considerable contribution of accelerated aging, and exploration of the mechanistic underpinnings of telomere attrition, one of the core pathophysiological hallmarks of accelerated aging could boost the development of new avenues for intervention in SZ. The longevity protein Klotho (KL) is reported to regulate the expression of key factors like telomeric repeat-binding factor. We tested the cross-sectional association between KL levels, its longevity genetic variant KL-VS and telomere length in schizophrenia, including 240 patients and 243 healthy controls (HCs).

Quantifying the morphological variations of internal carotid artery in moyamoya angiopathy.

Aim: Moyamoya angiopathy (MMA) is characterised by the progressive narrowing and subsequent development of collateral blood vessels in the distal internal carotid artery (ICA) and its branches. This study investigates the influence of loss in ICA tortuosity and the role of morphological parameters of ICA subsegments in MMA.

Methods: This study utilised the 3D morphometric analysis of ICA models and its subsegments developed from magnetic resonance angiography to evaluate morphological variations in MMA.