Fever of Unknown Origin in a Renal Transplant Recipient.

A syndrome of exaggerated lymphocytic proliferation and activation, called hemophagocytic lymphohistiocytosis (HLH) can occur primarily due to genetic mutation, in children and secondary to infection, malignancy or autoimmunity in adults. It is characterized by a misdirected activation of immune system, which causes cytokine release from macrophages and cytotoxic cells, in an uncontrolled fashion. Most treatment protocols are formulated for primary hemophagocytic histiocytosis, which occurs in children, whereas awareness and therapeutic guidelines for the secondary form of the disease which affects predominantly the adults is limited.

Post-Diarrheal Acute Kidney Injury During an Epidemic in Monsoon - A Retrospective Study from a Tertiary Care Hospital.

Background: Acute kidney injury (AKI) is a severe complication of acute diarrheal diseases; however, there is limited data on post-diarrheal AKI (PD-AKI) epidemiology and outcomes. This study aimed to investigate the clinicodemographic profile and outcomes of PD-AKI in our hospital.

Materials And Methods: We retrospectively analyzed data from 93 patients admitted with PD-AKI during a diarrheal illness epidemic.

Donor-Derived Cell-Free DNA and Active Rejection in Renal Allografts.

Background: Renal allograft rejection contributes to significant morbidity and graft loss. In this setting, early detection of rejection is of paramount importance, which currently relies on histopathology. A reliable non-invasive marker to predict rejection would make surveillance and decision-making easier.

Rhabdomyolysis-associated Acute Kidney Injury.

Introduction: Acute kidney injury represents one of the most severe complications of rhabdomyolysis.

Methods: We performed a prospective observational study to analyze the etiology, clinical manifestations, laboratory profile, and outcome in patients with biopsy-proven pigment-induced nephropathy between January 2017 and September 2019. History, clinical examination findings, laboratory investigations, and outcomes were recorded.

Clinical Profile, Histopathology, and Outcomes in Infection-Related Glomerulonephritis - Single-Center Experience.

Background: Infection-related glomerulonephritis (IRGN) is an important source of renal morbidity with adverse outcomes in adults. Data from large centers in India is lacking on this common, yet poorly understood entity.

Materials And Methods: We performed a prospective observational study of all patients diagnosed with IRGN at our center over a 3-year period between 2017 and 2019.