Publications by authors named "Muhammad Nadim Akbar Khan"
Objective: To determine the frequency of suspected dysregulated renal tubular handling of filtered glucose, and its association with blood glucose levels in type 2 diabetes mellitus.
Methods: The analytical, cross-sectional study was conducted from November 2022 to June 2023 at the Department of Medicine along with the Department of Pathology and Biochemistry, Pakistan Railway Hospital, Islamic International Medical College, Rawalpindi, Pakistan, and comprised diabetics aged 19-80 years. Blood and urinary glucose were assessed at the point of contact.
Article Synopsis
- The study aimed to analyze the role of serum arginase levels as an early predictor for pregnancy-related hypertension and preeclampsia in women between 20-25 weeks of gestation.
- A total of 90 pregnant women were divided into three groups based on their health status: a control group (no complications), a group with pregnancy-induced hypertension, and a group with preeclampsia, with various serum markers measured for each group.
- Results showed significant differences in serum arginase and other markers among the groups, indicating that elevated serum arginase levels could potentially help identify women at risk for hypertensive disorders during pregnancy.
Objectives: To determine the association of triglyceride-glucose index with homeostasis model assessment of insulin resistance in type 2 diabetes mellitus patients, and to determine the association of triglyceride-glucose index with urinary albumin-to-creatinine ratio for predicting diabetic nephropathy.
Methods: The observational, cross-sectional study was conducted from September 2021 to September 2022 at the Department of Chemical Pathology, Pakistan Railway Hospital, Rawalpindi, Pakistan and comprised recently-diagnosed type 2 diabetes mellitus patients. Recorded data included age, gender, vitals, diabetes duration, body mass index and other pertinent demographic and clinical information.
Low amniotic fluid index in high-risk pregnancy and poor apgar score at birth.
J Coll Physicians Surg Pak
October 2008
Article Synopsis
- - The study aimed to evaluate the effectiveness of the Amniotic Fluid Index (AFI) at or below 5 cm as an indicator of negative birth outcomes in high-risk pregnancies.
- - Researchers conducted a cross-sectional analysis involving 100 pregnant women, comparing outcomes based on their AFI levels and calculating newborn Apgar scores to assess health status at birth.
- - Results revealed that low AFI was not a reliable predictor of adverse outcomes, with only 57.1% sensitivity and 51.3% specificity, suggesting that AFI should not be used as a screening tool for high-risk pregnancies.
Impact of new diagnostic criteria of diabetes mellitus.
J Coll Physicians Surg Pak
June 2007
Article Synopsis
- - The study aimed to compare the diagnosis frequency of diabetes using different fasting plasma glucose (FPG) cut-off points, specifically > or = 7.0 mmol/L against the previous > or = 7.8 mmol/L.
- - Conducted at the Armed Forces Institute of Pathology in Rawalpindi, the research involved 5,250 subjects, with a subset of 301 symptom-free individuals undergoing a glucose tolerance test to assess the accuracy of the new FPG threshold.
- - Results showed that lowering the FPG cut-off to 7.0 mmol/L increased diagnosed diabetes cases from 35% to 42%, with significant sensitivity and specificity rates indicating improved early diabetes identification potential.