MOF-Based Composite Materials for Supercapacitors: Design, Performance, and Challenges.

Composite materials based on metal-organic frameworks (MOFs) are appealing materials for supercapacitor electrodes because of their high specific surface area, large pore volume, and range of adjustable topologies. This review paper thoroughly examines the synthesis techniques, morphological traits, and problems associated with pristine MOFs. Then, this article focuses on the synthesis techniques of MOF-based composites that include MOF/carbon, MOF/metal oxide, MOF/conducting polymer, MOF-derived carbons, and multimetallic MOF composites.

Exploring novel of 1,2,4-triazolo[4,3-a]quinoxaline sulfonamide regioisomers as anti-diabetic and anti-Alzheimer agents with in-silico molecular docking simulation.

In this study, a novel series of 1,2,4-triazolo[4,3-a]quinoxalines containing a sulfonamide moiety was designed and synthesized through regioselective synthesis from 2 and/ 3-hydrazino-6-(pyrrolidin-1-ylsulfonyl)quinoxaline derivatives 5 and 7. The structures of two isomers were confirmed and characterized by IR,H NMR,C NMR, and elemental analysis data. The synthesized 1,2,4-triazolo[4,3-a]quinoxaline derivatives 8-13 were evaluated for their antidiabetic activities by targeting α-amylase and α-glucosidase, as well as for their anti-Alzheimer activity by targeting acetylcholinesterase (AChE) at a concentration of 100 µM.

Novel Azo dyes containing a hydrazide-hydrazone moiety for dyeing polyester fabric.

Novel azo dyes containing a hydrazide-hydrazone moiety linked to the benzothiazole nucleus are synthesized effectively in this study. The primary purpose of the study was to identify the best dyeing parameters, such as shade, temperature, pH, and time, in order to better understand the behaviour of dispersed dyes during polyester dyeing. To achieve excellent colour strength in value (K/S = 26), the ideal dyeing conditions for disperse dye 4 were 30 min, pH of 8, and 110 °C at shade 3%.

A new class of anti-proliferative activity and apoptotic inducer with molecular docking studies for a novel of 1,3-dithiolo[4,5-]quinoxaline derivatives hybrid with a sulfonamide moiety.

A new series of 6-(pyrrolidin-1-ylsulfonyl)-[1,3]dithiolo[4,5-]quinoxaline-2-ylidines 10a-f, 12, 14, 16, and 18 were designed, synthesized, and evaluated for their anticancer activity. The structures of the novel compounds were systematically characterized by H NMR, C NMR, and elemental analysis. The synthesized derivatives were evaluated for their antiproliferative activity against three human cancer cell lines (HepG-2, HCT-116, and MCF-7) with more sensitivity to MCF-7.

Role of Krebs von den Lungen-6 (KL-6) in Assessing Hypersensitivity Pneumonitis.

Background: Hypersensitivity pneumonitis (HP) is an increasingly recognized form of diffuse parenchymal lung disease. Krebs von den Lungen-6 (KL-6) is now classified as a human MUC1 mucin protein, and regenerating type II pneumocytes are the primary cellular source of KL-6/MUC1 in the affected lungs of patients with interstitial lung diseases (ILD). Serum KL-6/MUC1 levels have been demonstrated to be useful for the evaluation of various ILD.

Optimizing Immunosuppressive Regimens Among Living-Donor Renal Transplant Recipients.

Objectives: We review different immunosuppressant protocols used for living-donor kidney transplant recipients at our center.

Materials And Methods: Many prospective randomized studies from our center have been reported between March 1976 and 2016, with more than 2700 renal transplant procedures conducted. The first study was a prospective randomized trial of azathioprine versus cyclosporine.