Correction: Hybrid thiazolyl-benzylidene-phenol metal complexes as novel chemotherapeutic agents with anti-topoisomerase I activity in human breast carcinoma: synthesis, and studies.

[This corrects the article DOI: 10.1039/D5RA00889A.].

Hybrid thiazolyl-benzylidene-phenol metal complexes as novel chemotherapeutic agents with anti-topoisomerase I activity in human breast carcinoma: synthesis, and studies.

A new ligand, benzylidene-phenol-thiazole (HBHTP), and its M(ii) complexes (M = Co, Ni, Cu, or Zn) were synthesized using a hybrid pharmacophore approach. The structures were optimized using density functional theory (DFT) calculations. MTT cytotoxicity assay showed that CuBHTP was the most effective and least toxic to normal cells, with the highest toxicity against MCF-7 cells.