Publications by authors named "Molly A Chakraborty"
Background: We conducted a prospective, phase II trial in which a radiation tumor bed boost was delivered preoperatively instead of the standard postoperative approach for breast cancer patients. We hypothesized that a preoperative boost would result in a lower rate of re-excision and a shorter duration of locoregional therapy compared with a postoperative boost.
Methods: Patients in this trial (NCT04871516) received a boost of 13.
Radiation therapy (RT) is a common component of breast cancer treatment. Chronic radiation dermatitis (CRD), defined as occurring after or extending beyond 90 days following the completion of RT, can be progressive and irreversible and manifest as changes in skin pigmentation, fibrosis, telangiectasia, ulceration, necrosis, and contribute to the development of cutaneous malignancy. There is limited existing research on the incidence, management approaches, and prevention strategies for CRD.
View Article and Find Full Text PDFProton Reirradiation for High-Risk Recurrent or New Primary Breast Cancer.
Cancers (Basel)
December 2023
Article Synopsis
- * Many patients, especially those with aggressive features, could benefit from reirradiation (reRT), which has typically been avoided due to concerns about severe side effects.
- * Proton therapy offers a promising alternative for reRT, as it minimizes harm to healthy tissues and could enhance control of regional disease in recurrent or new primary breast cancer cases.