Background: This systematic review and meta-analysis aims to evaluate the diagnostic utility of [F]Fluorodeoxyglucose ([F]FDG) PET/CT and [F]FDG PET/MRI in preoperative locoregional staging of bladder cancer (BC).
Methods: A comprehensive search of PubMed and Scopus databases was conducted up to February 26, 2025, to collect and analyze diagnostic accuracy parameters. Statistical analyses, including publication bias assessment, interstudy heterogeneity evaluation, and effect size adjustment, were performed using Stata software, with a significance threshold set at p < 0.
A 74-year-old man with metastatic castration-resistant prostate cancer underwent 2 cycles of [ 177 Lu]Lu-prostate-specific membrane antigen (PSMA) therapy. Despite declining prostate-specific antigen (PSA) levels and pain relief throughout the first 4 months of [ 177 Lu]Lu-PSMA therapy, follow-up [ 68 Ga]Ga-PSMA PET/CT revealed progressive skeletal involvement. A bone marrow biopsy confirmed fulminant metastatic castration-resistant prostate cancer infiltration.
View Article and Find Full Text PDFNucl Med Commun
August 2025
[68Ga]Ga-DOTA-Tyr3-octreotate ([68Ga]Ga-DOTATATE) is an established somatostatin receptor imaging agent that has demonstrated superior efficacy in visualizing neuroendocrine tumors (NETs) and meningiomas compared with traditional [ 111 In]In-octreotide imaging. Despite its enhanced affinity and sensitivity, [68Ga]Ga-DOTATATE imaging is not without challenges. To date, numerous diagnostic pitfalls and false-positive findings have been reported.
View Article and Find Full Text PDFColorectal cancer is a common malignancy, with the liver being the most frequent site of metastases. [F] Fluorodeoxyglucose ([F]FDG) positron emission tomography/computed tomography (PET/CT) has emerged as a valuable tool in detecting and evaluating liver metastases and extrahepatic disease. Herein, we present a case of a 76-year-old male with colorectal cancer associated with lung and liver metastases.
View Article and Find Full Text PDF68 Ga-FAPI has been introduced recently in many nuclear medicine centers. Many pitfalls have been discussed previously. However, not all pitfalls are currently addressed in the literature.
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