Publications by authors named "Mohammad Shehadeh"

Introduction And Importance: Atypical teratoid rhabdoid tumor (ATRT) is a rare and aggressive central nervous system malignancy. It primarily affects infants and young children, with adult cases being exceptionally uncommon. This case highlights the diagnostic and management challenges posed by ATRT in a 38-year-old pregnant woman.

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. Low- and middle-income countries (LMICs) face persistent challenges in reducing pediatric mortality, particularly in emergency settings. Simulation-based training (SBT) offers a practical solution to improve pediatric emergency care by enhancing healthcare providers' skills and clinical decision-making.

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Background: Respiratory syncytial virus (RSV) poses a significant respiratory health risk to senior citizens, contributing substantially to hospitalizations and mortality. With the recent approval of three RSV vaccines for the elderly, it is critical to understand the factors that can shape the RSV vaccination attitudes to inform public health strategies that can enhance uptake among this vulnerable population.

Objectives: This study aimed to investigate the potential factors that could influence the attitudes toward RSV vaccination among senior citizens in Arab countries.

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Background: Urethral diverticulum is a sac-like dilation that extends from the urethral lumen and is connected to it. It can either be congenital or acquired, with the latter being more common. The development of calculi is rare in such patients.

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Teratomas are germ cell tumors that arise from the derivatives of the three germ cell layers. They are categorized into subtypes by the extent of maturation, with mature teratomas being the most common subtype. While they can arise in various extragonadal regions, including the retroperitoneum, their occurrence in the retroperitoneal space is extremely rare.

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Article Synopsis
  • DADA2 (deficiency of adenosine deaminase 2) is a rare genetic disorder caused by mutations in the ADA2 gene, mainly affecting children under 10 but can also occur in adults, leading to diverse clinical symptoms across multiple organ systems.
  • An 18-year-old female with DADA2 presented with symptoms including flank pain, fever, and kidney issues, with genetic testing confirming the diagnosis.
  • Recognizing DADA2's varied manifestations is crucial for timely diagnosis and treatment, especially in patients with unexplained kidney problems, which can significantly improve patient outcomes.
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Article Synopsis
  • * A case of a 10-year-old girl with chest pain led to the discovery of a large anterior mediastinal mass, which was successfully removed through surgery.
  • * These teratomas present diagnostic challenges due to vague symptoms and diverse imaging features, emphasizing the need for early detection and careful monitoring post-surgery.
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Ureteric duplication is a rare anomaly in the urinary tract, with an incidence of 0.5% to 3%. Bilateral double ureters are even rarer, occurring in 1 of 500 individuals.

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Article Synopsis
  • - Landau-Kleffner syndrome (LKS) is a rare condition causing language regression and abnormal EEG patterns; early recognition and intervention are crucial for effective management.
  • - A case study of an 8-year-old girl with language regression and suspected hearing loss revealed EEG abnormalities consistent with LKS, and treatment with speech therapy and valproic acid led to significant improvements.
  • - The report emphasizes the need for a multidisciplinary approach involving various specialists to diagnose and manage LKS, and calls for more research to improve treatment and outcomes for affected children.
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Bardet-Biedl syndrome (BBS) is a rare genetic disorder characterized by retinitis pigmentosa, polydactyly, type 2 diabetes mellitus, and obesity. This case report presents a 19-year-old male from Palestine with BBS, exhibiting delayed diagnosis and variable phenotypic expression. The patient had familial BBS history and presented with obesity, type 2 diabetes mellitus, retinitis pigmentosa, and cryptorchidism.

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The incidence of undescended testicles torsion in a 7-year-old is rare, making it a clinically unusual occurrence. Emphasizing the importance of thorough urogenital assessments in children, particularly in underserved communities, is critical to prevent serious complications like testicular gangrene.

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Renal lymphangiomatosis is a rare congenital condition characterized by the abnormal development of lymphatic channels in the kidney, resulting in cystic dilatations. While more commonly observed in children, it can occur in adults but is extremely rare. Clinical manifestations range from asymptomatic cases to symptoms such as abdominal pain, hypertension, and renal dysfunction.

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Introduction And Importance: Fibroepithelial vaginal polyps (FEPV) are rare mucosal polypoid lesions primarily found in adult women. However, FEPV in paediatric patients, especially beyond the neonatal period, is exceedingly uncommon. Documenting cases improves diagnosis and management.

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Purpose: The present study aimed to evaluate the quality of life of keratoconus patients residing in Nablus city, Palestine. Furthermore, we investigated the possible correlation between Pentacam topographic indices and the quality of life of patients with keratoconus.

Methods: This cross-sectional study evaluated keratoconus patients at An-Najah University Hospital in 2019, diagnosed through clinical examination and corneal tomography.

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Purpose: This article aims to evaluate how the subfoveal choroidal thickness (SFCT) and best-corrected visual acuity (BCVA) respond to the intravitreal injection of bevacizumab and to assess the correlation between these changes. It will also assess the use of the baseline SFCT as a predictor for BCVA changes in eyes of treatment-naive, diabetic macular edema (DME) patients.

Methods: This retrospective, consecutive case series comprised 59 eyes of 39 treatment-naive DME patients.

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Given the role the vascular endothelial growth factor (VEGF) plays in controlling and preserving the integrity of the vascular endothelium intravitreal administration of anti-VEGF agents may affect the risk of thromboembolic events. This is particularly noticeable in patients who are at risk for atherosclerosis. Here, we present one of the first case reports of transient ischemic attack (TIA) together with hypoventilation secondary to aflibercept injection.

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Background: Generally, complementary and alternative therapies (CAT) are accepted methods of treatment by patients with various types of conditions. Their use is becoming especially prevalent among patients with eye problems even in developed countries. Thus, we aimed to determine the pattern of use of CAT in this patient population, to identify the patient characteristics associated with the use of CAT, and to assess the types of CAT used.

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Purpose: The aim of this study is to evaluate the short anatomical and visual outcomes of scleral buckling surgery in relation to the pattern of presentation of rhegmatogenous retinal detachment (RRD) in the presence of different situations and risk factors.

Methods: A total of 206 eyes of 203 patients who underwent scleral buckling surgery for RRD were evaluated in this retrospective study. Information retrieved included patient demographics, duration of symptoms, and presenting vision, lens status, site of a retinal break, extent of retinal detachment, the involvement of the fellow eye, macular involvement, presence of lattice degeneration, and associated refractive errors.

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Background: Severe Retinopathy of Prematurity (ROP) is a serious vasoproliferative disorder that can affect extremely premature infants. It continues to be one of the most important preventable causes of blindness in children. Our study is aimed at finding the incidence of ROP and its association with some risk factors in Palestine.

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Background: Laser corneal refractive surgery suits, technology and nomograms are improving with time. This may improve the refractive and visual outcomes of the patients.

Objectives: To evaluate the safety, efficacy, stability, and predictability of wavefront-optimized photorefractive keratectomy and Laser-assisted keratomileusis in patients with myopia and myopic astigmatism over 1-year using WaveLight EX500 Excimer Laser machine.

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Purpose: To screen for keratoconus and potential associated risk factors in a tertiary student population sample.

Population And Methods: This cross sectional study included 1234 students attending An-Najah National University (Nablus, West Bank, Palestine), that were randomly selected from a total of 20,000 university students. 634 (51.

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Purpose: To present the results after simultaneous conventional photorefractive keratectomy combined with corneal collagen cross-linking for pellucid marginal corneal degeneration.

Methods: In this prospective, interventional case series, 6 patients (8 eyes) with pellucid marginal corneal degeneration were enrolled. All patients underwent simultaneous conventional photorefractive keratectomy combined with corneal collagen cross-linking; corneal epithelium was removed by transepithelial phototherapeutic keratectomy during treatment (Cretan protocol plus conventional photorefractive keratectomy).

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Purpose: To review the current literature on in vivo confocal microscopy anterior segment applications (cornea, conjunctiva, and glaucoma) and discuss its advantages in different pathological conditions.

Methods: Review of selected relevant literature on in vivo confocal microscopy and its different applications.

Results: In vivo confocal microscopy can be used to visualize most layers of the cornea and conjunctiva, providing excellent resolution.

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Background: Spondylotic vertebral artery (VA) compression is a rare cause of vertebrobasilar insufficiency and stroke.

Case Description: A 53-year-old man experienced multiple brief vertebrobasilar transient ischemic attacks (TIAs) and strokes, not apparently triggered by neck movements. Brain magnetic resonance imaging (MRI) documented consecutive infarcts, first in the left then right medial posterior inferior cerebellar artery (PICA) territories.

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Purpose: To report 3 cases of keratoconic patients who had progressive corneal topographic flattening during a 2-year follow-up period.

Methods: Case series.

Results: Three patients with bilateral keratoconus, each operated for advanced keratoconus in one of their eyes, were observed for possible progression of the disorder for a period of 2 years.

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