Immunoinformatic design of chimeric multiepitope vaccine for the prevention of human metapneumovirus (hMPV).

Background: Human metapneumovirus (hMPV) is a significant etiological agent of acute respiratory infections in children and immunocompromised individuals. Despite its growing clinical impact, no approved vaccines or targeted antiviral therapies are currently available.

Methods: An immunoinformatic approach was employed to design a chimeric multi-epitope vaccine candidate against hMPV.