Background: Metabolic and bariatric surgery (MBS) is an effective intervention for morbid obesity. Yet, rapid weight loss often indicates the early postoperative period, which can include substantial reductions in lean body mass. One Anastomosis Gastric Bypass (OAGB) is being used more frequently; however, data on the postoperative effects of whey protein supplementation in this specific procedure are still limited.
View Article and Find Full Text PDFMultiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system. Inflammasomes, particularly NLRP3 and AIM2, have been implicated in MS pathogenesis. Interferon-β (IFN-β) and Rituximab (RTX) are treatment agents for relapsing-remitting MS (RRMS), but their impact on inflammasome regulation remains unclear.
View Article and Find Full Text PDFAllergy Asthma Clin Immunol
May 2025
Background: Hyper-IgE Syndrome, also known as Job's syndrome, is a rare primary immunodeficiency disorder characterized by recurrent infections and elevated levels of immunoglobulin E. While respiratory and systemic manifestations have been more emphasized, dermatological manifestations in Hyper-IgE Syndrome also play a significant role in disease presentation.
Methods: This narrative review explores the dermatologic presentations of Hyper-IgE Syndrome in pediatric populations, including descriptions, associated symptoms/findings, and available treatment options.
The intragastric balloon (IGB) acts as a restrictive procedure with acceptable short-term weight loss outcomes and a low incidence of major complications. This systematic review and meta-analysis aimed to assess whether preoperative insertion of an IGB can reduce perioperative complications and improve weight loss outcomes following metabolic bariatric surgery (MBS). PubMed, Embase, Scopus, and Web of Science databases were searched using relevant keywords to include studies on IGB as a bridge before MBS.
View Article and Find Full Text PDFBackground: With the rise of artificial intelligence (AI) in medical education, tools like OpenAI's ChatGPT-4 and DALL·E 3 have potential applications in enhancing learning materials. This study aims to evaluate ChatGPT-4o's proficiency in recognizing bariatric surgical procedures from illustrations and assess DALL·E 3's effectiveness in generating accurate surgical illustrations.
Methods: Illustrations of six bariatric surgical procedures (One Anastomosis Gastric Bypass, Roux-en-Y Gastric Bypass, Single Anastomosis Duodeno-Ileal Bypass with Sleeve Gastrectomy, Sleeve Gastrectomy, Biliopancreatic Diversion, and Adjustable Gastric Banding) were sourced from the IFSO Atlas of Metabolic and Bariatric Surgery.
Background: While OAGB shows promise in the short to medium term, its long-term durability, weight trends, blood levels of metabolic factors and nutrients, and potential complications require further exploration through larger, longer-term studies. This study contributes to the growing body of evidence by reporting on the long-term outcomes of patients with severe obesity who underwent OAGB.
Methods And Patients: A retrospective study on prospectively collected data was conducted on a sample of 1917 patients who underwent OAGB between 2010 and 2019 and had a BMI ≥ 35 kg/m.
Background: Bariatric surgery patients may develop common bile duct stones, and the alterations in their anatomy present challenges in treating this condition. Methods such as laparoscopic bile duct exploration is impractical in many healthcare facilities, due to the absence of a choledochoscope. This study assesses the feasibility of laparoscopic exploration of the common bile duct using a disposable bronchoscope in these individuals.
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