Acute Tubulointerstitial Nephritis (ATIN) in Patient With Autosomal Dominant Polycystic Kidney Disease (ADPKD): A Case Report.

Autosomal dominant polycystic kidney disease (ADPKD) is characterized by diffuse renal cysts that secrete cytokines, which induce interstitial inflammation and fibrosis. Meanwhile, acute tubulointerstitial nephritis (ATIN) is characterized by inflammatory infiltrates in the interstitium, where kidney biopsy remains the mainstay for diagnosis. An 85-year-old male complained of fatigue, loss of appetite, and low-grade fever for a week.

Loin pain hematuria syndrome (LPHS) induced by pyelonephritis in diabetes mellitus female with brucellosis: a diagnosis of challenge.

Loin pain hematuria syndrome (LPHS) is an extremely rare disease with a prevalence of about 0.012% and is more common in women (approximately 70% of cases). The majority of cases present by the third decade of life, where the chronic loin pain varies in duration (ranging from minutes to a constant ache) and frequency (ranging from once or twice a year to incessant pain).

The clinical classification of patients with acute heart failure at emergency department and its relation with management and outcome: a cross sectional study from Syria.

Introduction: To compare the clinical characteristics and outcomes of patients with acute heart failure (AHF) according to the 2016 European Society of Cardiology (ESC) guidelines taking into account isolated right HF (RHF) with left HF (LHF) phenotypes. Volume status was assessed by the clinical manifestations and lung ultrasound (LUS). The secondary aim was to study the role of echocardiography in congestion based on LUS and their relations with outcomes.

Acute tubulointerstitial nephritis (ATIN) including drug-induced, tubulointerstitial nephritis and uveitis (TINU), ANCA-associated vasculitis (AAV), kidney- limited sarcoidosis, and hemolysis: a case series from Syria.

Background: This study aimed to detail acute tubulointerstitial nephritis (ATIN) patients, from relevant clinical manifestations to outcomes.

Methods: We reviewed ATIN patients between 2018 and 2022. All demographic data, labs, biopsy findings, treatment protocols, and outcomes were reported.

Spinal Cord Compression as the First Presentation of Primary Hyperoxaluria in a Patient With Kidney Failure: A Case Report and Literature Review.

A 50-year-old woman with kidney failure complained of back pain and an inability to walk. The medical history included hypothyroidism, nephrolithiasis, and resistant anemia aligned with several transfusions. The examination showed hepatosplenomegaly, lower limb weakness, absence of reflexes, and lack of sensations with a sensory level T6.

Antibiotic Lock Therapy (ALT) for the prevention of Catheter Related Blood Stream Infection (CRBSI) in neurological patients treated with Therapeutic Plasma Exchange (TPE).

•Catheter related blood stream infection (CRBSI) is associated with several debilitating consequences for patients and medical institutions.•Antibiotic lock therapy (ALT) significantly reduced the incidence of CRBSI in patients receiving therapeutic plasma exchange (TPE).•Antibiotic lock therapy (ALT) reduced the medical care costs•ALT should be considered an acceptable and reasonable approach for patients receiving TPE.

Status epilepticus resulted in rhabdomyolysis-induced AKI associated with hepatotoxicity induced by synergistic carbamazepine and diazepam: A case report.

Rationale: Rhabdomyolysis is a serious complication of status epilepticus (SE) caused by muscle cell damage and can lead to a life-threatening acute kidney injury (AKI).

Patient Concerns: A 35-year-old man with a history of seizures treated with 3 different antiepileptic drugs (carbamazepine, lamotrigine, and levetiracetam) presented with SE. The patient received 5 doses of diazepam to control the SE in another hospital and was transferred to our emergency due to AKI.

Autoimmune thyroid disease in patients with type 1 diabetes mellites: A cross-sectional study from Syria.

The present study aimed to investigate the occurrence of autoimmune thyroid disease (AITD) in patients with type 1 diabetes mellitus (T1DM) by the presence of antithyroid peroxidase (anti-TPO Ab). Furthermore, we studied the relationship of clinical and thyroid ultrasound (US) characteristics with anti-TPO Ab. This cross-sectional study was performed in Al- Mowasat and Al-Assad University Hospitals from 2021 to 2023.

Spontaneous hemorrhage of spinal epidural capillary hemangioma resulting in hyperacute neurologic deficit: A case report.

Introduction: Spinal epidural capillary hemangioma is a very rare variety of tumors, usually with a predilection for the thoracic spine.

Case Presentation: A 16-year-old female complained of hyperacute neurologic deficit progressed within hour, which presented by acute paraplegia, and loss of all sensations from her lower limbs up to her breasts. Neurologic exam revealed paralysis of lower limbs (0/5 on both legs) with a flaccid tone, absence of reflexes, weakness of the trunk with sensory level T4, bilateral flexion of plantar reflexes, and loss of sphincters' controls.

The correlation of lipid profile with subclinical and overt hypothyroidism: A cross-sectional study from Syria.

We proceeded with this study to investigate the relationship between hypothyroidism and lipid profile disturbance. A cross-sectional study at Al- Mowasat University Hospital in Damascus was conducted from March 2021 to March 2022, and included 324 adults. For each participant with abnormal thyroid stimulating hormone (TSH), free thyroxine (FT4) was requested.

The prevalence of dyslipidemia in patients on hemodialysis: a cross-sectional study from Syria.

Unlabelled: Dyslipidemia is an established risk factor for cardiovascular disease (CVD), which is the main cause of mortality among haemodialysis (HD) patients. We investigate the prevalence and characteristics of dyslipidemia in HD patients. Also, we aimed to study the prediction scores; Framingham risk score (FRS), and the atherosclerotic cardiovascular disease risk score; among this population.

The relationship between papillary thyroid carcinoma and preoperative TSH level: A cross-sectional study from Syria.

Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer, and thyroid stimulating hormone (TSH) is the major growth factor for thyroid cells. It is also an available, inexpensive test and performed routinely while evaluating thyroid nodules. Yet the relationship between TSH levels and PTC is still controversial.

Determinants of hyperphosphatemia and its relation with hemoglobin levels among hemodialysis patients in two hospitals from Syria: a prospective cross-sectional study.

Unlabelled: Hyperphosphatemia and anemia were both associated with several complications in chronic kidney disease (CKD) patients. This study aimed to determine the risk factors of hyperphosphatemia and its relation with anemia among hemodialysis (HD) patients. Secondly, it aimed to determine the prevalence of hyperphosphatemia and anemia.

Antinuclear antibodies positive acute nonfulminant hepatitis A associated with acute renal failure and hives: a case report.

Unlabelled: Acute hepatitis A (AHA) is a self-limited illness. While the prognosis for hepatitis A is generally good, complications with acute renal failure can have a negative impact.

Presentation Of Case: A 60-year-old male was admitted due to fever and malaise for a week, accompanied by jaundice and reduced urine output over the past 3 days.

Association of subclinical hypothyroidism with metabolic syndrome components in a group of apparently healthy Syrians: a retrospective cross-sectional study.

Unlabelled: Thyroid disorders were reported to be associated with various diseases, particularly dyslipidemia. This study aimed to assess the prevalence of thyroid disorders in a group of apparently healthy Syrians and investigate the relationship between subclinical hypothyroidism and metabolic syndrome (MetS).

Methods: A retrospective, cross-sectional study was performed at Al-Assad University Hospital.

Delayed acyclovir therapy for disseminated varicella zoster in an adult kidney transplant recipient: a case report and literature review.

Unlabelled: Kidney transplant recipients are at increasing risk for reactivation of varicella-zoster virus (VZV) infection.

Presentation Of Case: A 31-year-old male was admitted with fever, chest pain, and dyspnea. Also, the complaints accompanied by generalized maculopapular, vesicular, hemorrhagic, itching, and painful rash with pustules and crusts on an erythematous base fill the entire body for the last 10 days.

Primary membranoproliferative glomerulonephritis in a child with down syndrome complicated with CVA: A case report.

Introduction: Down syndrome (DS) is a genetic disorder that affects multiple organs but glomerular lesions were reported only in case reports such as focal segmental glomerulosclerosis (FSGS), and Membranoproliferative glomerulonephritis (MPGN).

Case Presentation: A 14-year-old male child with DS was presented with generalized edema over three months. Laboratory tests revealed nephrotic syndrome (NS) and urinary tract infection (UTI).

MELAS syndrome with rare manifestations misdiagnosed as vasculitis in the absence of lactic acidosis: A case report.

Introduction: The syndrome of mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS) is one of the most common inherited mitochondrial disorders.

Presentation Of Case: A 33- year-old male was admitted due to edema, urinary retention, and reduce urinary output. The medical history included a pigmentary retinopathy (PR) at age of 22 and uveitis at age of 30, which were both treated with prednisolone.

Anterior displacement of an avulsed posterio-latero-central tibial plateau fracture repaired with Herbert screws.

Introduction: Tibial plateau fractures are very complex articular fractures with a rare incidence of approximately 10.3%. These fractures may constitute a severe injury to the knee joint and other complications.

Resistant hypertension and PRES syndrome induced by carbamazepine in a patient with SLE: A case report and literature review.

Introduction: Several conditions of resistant hypertension (RHTN) have been suggested and are often associated in the same patient. Approximately 75% of patients with posterior reversible encephalopathy syndrome (PRES) have moderate to severe HTN at presentation.

Case Presentation: A 26- year old SLE-patient presented with seizures followed by confusion and cortical blindness, in the context of emergent HTN and MRI revealed PRES syndrome.

Successful treatment of Gustilo type 3C open tibial fracture with a massive muscles and soft tissues wasting: A case report.

Introduction And Importance: Gustilo-Anderson type 3 open tibial fractures are commonly accompanied by extensive damage and serious complications, especially in types 3B and 3C.

Case Presentation: A 25-year-old male was transferred after motor vehicle accident and the emergent choice was an above-knee amputation in other two hospital. A left open distal tibial fracture (Gustilo type 3C) with a wide and contaminated soft tissues defect, that extended from the knee to the midfoot, is accompanied by wasting of the anterior compartment muscles and ruptured of the anterior tibial artery.

The correlation of 25-hydroxyvitamin D with BMI and lipid profile: A retrospective cohort study of Syrian patients.

Background: This study aims to identify the prevalence of 25OHD deficiency in Syrian patients and investigate the relationship with obesity and lipid profile.

Methods: A retrospective cohort study consisted of 201 patients of age >10 years, who referred to Al Assad and Al Mouwasat University Hospitals, Damascus, Syria from Oct/2020 to Oct/2021. The data was analyzed by using linear regressions and produced a matrix of correlations with significant equations between study variables.