Publications by authors named "Mohamed Bakloul"
Safety and efficacy of transcatheter correction of sinus venosus defect using 70-100mm-long partially covered Optimus-CVS® XXL stents compared with surgery: The OPTIVENOSUS study design.
Arch Cardiovasc Dis
September 2025
Background: Transcatheter correction of sinus venosus defect provides a less invasive alternative to open-heart surgery.
Aim: To evaluate the safety and efficacy of 70-100mm-long partially covered balloon-expandable Optimus-CVS® XXL stents (AndraTec, Koblenz, Germany), specifically designed for sinus venosus defect repair, compared with surgical intervention.
Methods: OPTIVENOSUS is a French nationwide multicentre prospective comparative cohort study of patients with indications for sinus venosus defect correction (May 2023 to February 2031).
Objective: To assess the success rate of patent ductus arteriosus (PDA) transcatheter closure in preterm infants and to describe the nature of procedural adverse events and short-term clinical status.
Study Design: All the preterm infants with PDA transcatheter closure were evaluated retrospectively between July 2019 and March 2023 in a single level III neonatal intensive care unit in France. The procedure was performed in the catheterization laboratory using venous canulation.
Systematic Electrophysiological Study Prior to Pulmonary Valve Replacement in Tetralogy of Fallot: A Prospective Multicenter Study.
Circ Arrhythm Electrophysiol
June 2023
Background: Ventricular arrhythmias and sudden death are recognized complications in tetralogy of Fallot. Electrophysiological studies (EPS) before pulmonary valve replacement (PVR), the most common reintervention in tetralogy of Fallot, could potentially inform therapy to improve arrhythmic outcomes.
Methods: A prospective multicenter study was conducted to systematically assess EPS with programmed ventricular stimulation in patients with tetralogy of Fallot referred for PVR from January 2020 to December 2021.
Article Synopsis
- - The study focuses on the management of anomalous aortic origin of a coronary artery, which can be linked to sudden death in young individuals, especially those with an inter-arterial course.
- - Over a 25-year period, 100 patients were diagnosed, with higher rates of syncope and sudden death among those with an inter-arterial course compared to others (23.4% vs 0%).
- - Surgical repair was performed on 61 patients, all of whom had the inter-arterial course and were asymptomatic after an average follow-up of about 5 years, suggesting that surgical intervention is a viable option even for asymptomatic cases.
Background: Abnormal coronary pattern may complicate coronary transfer during arterial switch operation.
Objective: To evaluate the accuracy of echocardiography in assessing the anatomy of coronary arteries in neonates with transposition of the great arteries, and determine impact on outcomes.
Methods: We conducted a retrospective analysis of data in neonates with transposition of the great arteries.
Article Synopsis
- Balanced chromosomal rearrangements often have no noticeable effects on individuals, but they can sometimes lead to abnormal traits, as seen in a case study of a 4-year-old boy with supravalvular aortic stenosis (SVAS).
- The boy's karyotype revealed a balanced paracentric inversion on chromosome 7, and advanced sequencing techniques identified a disruption in a specific gene that caused his condition.
- This case emphasizes the limitations of common diagnostic tests like array CGH, suggesting that future use of whole-genome sequencing (WGS) should involve analyzing structural variations to better detect rare genetic disruptions.
To assess the outcomes of neonates prenatally diagnosed with ventricular asymmetry and not operated on within the neonatal period and to determine the risk factors for left heart obstruction occurrence at follow-up. All neonates with prenatal asymmetry of the ventricles, diagnosed from August 1993 to July 2015, not operated on within the neonatal period, were retrospectively included in the study. Left heart echocardiographic measurements at birth and at last follow-up were collected and compared.
View Article and Find Full Text PDFBackground: Percutaneous pulmonary valve implantation (PPVI) is a routine treatment for dysfunctional right ventricular outflow tract. Infective endocarditis (IE) is a major concern.
Aim: To report French experience with the Melody™ valve (Medtronic Inc.
Background: Coronary artery aneurysms (CAA) are serious complications of Kawasaki disease (KD). Optical coherence tomography (OCT) is a high-resolution intracoronary imaging modality that characterizes coronary artery wall structure. The purpose of this work was to describe CAA wall sequelae after KD.
View Article and Find Full Text PDFArticle Synopsis
- Late presentation of abnormal origin of coronary artery from the pulmonary artery (ACAPA) is rare and often involves collateral development, leading to mild symptoms but potential for sudden cardiac death.
- A study reviewed cases from 1976 to 2011, identifying 10 patients diagnosed with ACAPA between ages 1.1 to 64, with most undergoing successful surgical treatment.
- Noninvasive imaging methods like echocardiography can effectively diagnose late-presenting ACAPA, and surgical implantation into the aorta is shown to improve outcomes and reduce ischemia-related risks.