The Effect of the Thickness of Uterine Muscle at Placenta Attachment on Postpartum Blood Loss.

Objective: This study aimed to investigate the relationship between the thickness of the uterine muscle layer at placenta attachment and postpartum hemorrhage, and to evaluate the predictive value of this thickness in identifying high-risk patients. It provides a theoretical basis for early identification and screening of pregnant women at high risk of postpartum hemorrhage, and reduces the occurrence of serious complications of postpartum hemorrhage.

Method: A total of 378 pregnant women admitted to the Second People's Hospital of Shantou City from January to December 2021 were enrolled in this study.

Vasopressin-induced stimulation of the Na(+)-activated K(+) channels is responsible for maintaining the basolateral K(+) conductance of the thick ascending limb (TAL) in EAST/SeSAME syndrome.

The renal phenotype of EAST syndrome, a disease caused by the loss-of-function-mutations of Kcnj10 (Kir4.1), is a reminiscence of Gitelman's syndrome characterized by the defective function in the distal convoluted tubule (DCT). The aim of the present study is to test whether antidiuretic hormone (vasopressin)-induced stimulation of the Na(+)-activated 80-150pS K(+) channel is responsible for compensating the lost function of Kcnj10 in the thick ascending limb (TAL) of subjects with EAST syndrome.