Prognostic factors for metastatic gastrointestinal stromal tumors treated with cytoreductive surgery: a retrospective cohort study.

Background: Cytoreductive surgery (CRS) may benefit patients with metastatic gastrointestinal stromal tumors (GISTs) treated with tyrosine kinase inhibitors (TKIs). However, there is insufficient evidence on prognostic factors for metastatic GISTs undergoing CRS.

Methods: This study reviewed metastatic GISTs that underwent CRS after receiving TKIs in our center from April 2014 to December 2023.

Burnout in emergency medicine physicians: A meta-analysis and systematic review.

Background: Physician burnout has been a global problem that affects severely the mental status among doctors, especially in emergency medicine (EM). However, few studies have focused on emergency medicine physicians, and the published data are inconsistent. Thus, this meta-analysis is performed to systematically evaluate the prevalence of burnout among emergency medicine physicians.

[Effect of Runing II on expression of vascular endothelial growth factor in transplanted tumor of mammary cancer MA-891 in TA2 mice].

Objective: To study the effect of Runing II on expression of vascular endothelial growth factor (VEGF) in transplanted tumor of mammary cancer MA-891 in TA2 mice.

Methods: The MA-981 mice mammary cancer cell cultivated in vivo was inoculated into the right axilla subcutaneously of TA2 mice to establish the transplanted tumor model, which were treated with Runing II.

Results: Runing II could inhibit the growth of transplanted tumor and the occurrence of lung metastasis (P < 0.