Deep learning-based allergic rhinitis diagnosis using nasal endoscopy images.

Allergic rhinitis typically has edematous and pale turbinates or erythematous and inflamed turbinates. While traditional approaches include using skin prick tests (SPT) to determine the presence of AR, It is often not related to actual symptoms, and it is an invasive test. We use deep learning to analyze nasal endoscopy images to investigate a quantitative method for diagnosing allergic rhinitis.

Roasted Inhibits Aβ25-35-Induced Oxidative Stress in Neuronal Cells by Activating the Nrf2/HO-1 and AKT/CREB/BDNF Pathways.

(1) Background: (AM) has antioxidant and anti-inflammatory effects, but its specific mechanism of action in the brain is still unclear. In this study, we developed a roasting process to maximize the cognitive improvement impact of AM. We focused on enhancing physiological activity to enhance the brain neuron protection effect and alleviate neuronal damage caused by neurodegenerative diseases.

exhibits anti-neuroinflammatory potential against beta-amyloid-induced toxicity in microglia cells.

Background/objectives: (PG) is used in traditional oriental medicine to treat several ailments.

Methods: The study investigated the anti-inflammatory and neuroprotective effects of PGW () extract in Aβ25-35-induced inflammation in BV2 microglia cells.

Result: PGW demonstrated significant inhibition of nitric oxide (NO) production, with reductions of 30.

Inhibition by components of of 3CLpro and HCoV-OC43 proliferation.

Coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). 3CLpro is a key enzyme in coronavirus proliferation and a treatment target for COVID-19. and , compounds - from had inhibitory activity and binding affinity for 3CLpro.

Hydrophilic Versus Lipophilic Statin Treatments in Patients With Renal Impairment After Acute Myocardial Infarction.

Background Hydrophilic and lipophilic statins have similar efficacies in treating coronary artery disease. However, specific factors relevant to renal impairment and different arterial pathogeneses could modify the clinical effects of statin lipophilicity, and create differences in protective effects between statin types in patients with renal impairment. Methods and Results A total of 2062 patients with acute myocardial infarction with an estimated glomerular filtration rate <60 mL/min per 1.

Antioxidant and Anti-Melanogenic Activities of Heat-Treated Licorice (Wongam, × ) Extract.

Melanin is a brown or black pigment that protects skin from ultraviolet radiation and reactive oxygen species (ROS). However, overproduction of melanin is associated with lentigines, melasma, freckles and skin cancer. Licorice has shown antioxidant, anti-tumor, anti-platelet, anti-inflammatory and immunomodulatory activities and is used as a natural treatment for skin whitening.

Neuroprotective Effects of Flower Extract against Oxidative Stress-Induced Apoptosis in Neuronal Cells and Mice.

L. is a perennial plant of the family Asteraceae, and its flower is known to contain flavonoids with various bioactivities. We evaluated the effect of L.

Renal dysfunction is associated with decline of cognitive function in community-dwelling older adults: Korean frailty and aging cohort study.

Background: Cognitive decline is common in older adults. Similarly, the prevalence of renal dysfunction is also increased in the elderly population. We conducted this study to clarify the relationship between renal dysfunction and decline of cognitive function in community-dwelling elderly population.

Radiation safety: a focus on lead aprons and thyroid shields in interventional pain management.

C-arm fluoroscopy is useful equipment in interventional pain management because it helps to guide correct needle targeting for the accurate injection and drug delivery. However, due to increased use of C-arm fluoroscopy in various pain procedures, the risk of radiation exposure is a significant concern for pain physicians. The harmful biological effects of ionizing radiation on the human body are well known.