Publications by authors named "Michael Ilan"

Introduction: A new implantable cardioverter-defibrillator (ICD) lead with a polyurethane cover added for improved long-term reliance was investigated in a post-market study.

Methods: The prospective BIO|MASTER Pamira study is designed to evaluate the new Pamira ICD lead in patients undergoing de-novo ICD or cardiac resynchronization therapy (CRT-D) implantation. We report first data from implantation and 6-month follow-up.

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Introduction: Use of implantable loop recorder (ILR) for the diagnosis and documentation of cardiac arrhythmia has gained popularity during the last decade. Most ILRs are accompanied by remote monitoring (RM) devices, which allow automated daily interrogations of the ILR. These transmit arrhythmic or pause alerts to the treating clinic, enabling timely medical attention and treatment.

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  • Ventricular arrhythmias (VAs) are uncommon but can occur after electrical cardioversion (ECV) for atrial fibrillation (AF), with an incidence of about 0.2% based on a study of nearly 12,000 ECV procedures.
  • The study involved 23 patients who experienced VAs within 10 days of ECV, with most cases developing 28.5 hours after the procedure, and a significant number had underlying health issues like congestive heart failure.
  • The findings suggest that while VAs post-ECV are rare, they can be life-threatening, especially in patients with certain risk factors, indicating that careful monitoring is essential for these individuals.
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  • Current guidelines recommend implantable cardioverter-defibrillators (ICDs) for all patients with symptomatic heart failure and low left ventricular ejection fraction, but many may not benefit from them.
  • The study evaluated the feasibility of using the MADIT-II-based Risk Stratification Score (MRSS) to differentiate patients and gauge their likely survival benefits from ICDs.
  • Results indicated that among 2,177 patients, different MRSS risk groups had varying survival benefits from ICDs, suggesting that this score can help identify who might actually benefit from prophylactic ICD implantation.
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  • A novel 3D mapping system, KODEX-EPD, was evaluated for its accuracy in mapping the left atrium during pulmonary vein isolation compared to standard CT images in 15 patients.
  • The study found very high correlation between measurements from both systems, with a minor average difference of 3.5 mm in anatomical dimensions.
  • Despite some discrepancies in the detection of specific veins, the KODEX-EPD system demonstrated effective and efficient cardiac mapping capabilities.
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  • The study examined the effects of the COVID-19 lockdown in March/April 2020 on physical activity and arrhythmia issues in heart failure (HF) patients using cardiac resynchronization therapy (CRT) devices.
  • Results showed a significant decrease in activity levels (mean -6.5%), an increase in atrial high rate episodes (AHRE) by 17%, and a 75% drop in follow-up rates during the lockdown.
  • Key predictors for these changes included pre-lockdown activity levels, left ventricular ejection fraction (LVEF), NYHA class, and a history of atrial fibrillation among the patients.
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Aims: The aims of this study is to characterize the transvenous lead extraction (TLE) population with active (A) compared with passive fixation (PFix) leads and to compare the safety, efficacy, and ease of extracting active fixation (AFix) compared with PFix right atrial (RA) and right ventricular (RV) leads.

Methods And Results: The European Lead Extraction ConTRolled Registry (ELECTRa) was analysed. Patients were divided into three groups; those with only AFix, only PFix, and combined Fix leads.

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  • Many tachy-brady syndrome (TBS) patients receive permanent pacemakers (PPMs) as a precautionary treatment to support their anti-arrhythmic drug therapy aimed at maintaining sinus rhythm, even when they are not experiencing symptomatic bradycardia.
  • A retrospective study involving 119 TBS patients found that a majority had significant pacing use, with predictors like severe sinus bradycardia and certain treatments (like amiodarone) being linked to higher pacing use.
  • The study concluded that most TBS patients can maintain sinus rhythm with AAD therapy and substantial pacing, suggesting that preventive PPM implantation is beneficial, while only a small percentage progressed to permanent atrial fibrillation.
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  • Patients with left ventricular dysfunction and prolonged QRS on ECG are at a higher risk for heart failure and death, highlighting the need for resynchronization therapy.
  • A study followed 178 patients, finding that 16% had significant QRS prolongation, with older age, larger heart measurements, and wider baseline QRS linked to this change.
  • The research indicates that delayed QRS prolongation is strongly associated with increased mortality and heart failure hospitalizations, suggesting the importance of regular monitoring in these patients.
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  • * The research reviewed 48 definitive cases of lead perforation, finding that conservative management led to more complications, especially cardiac tamponade, compared to early lead revision.
  • * The conclusion suggests that early lead revision may be the better management strategy, particularly for patients on antiplatelets or anticoagulants.
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Background: Limited information exists about detailed clinical characteristics and management of the small subset of Brugada syndrome (BrS) patients who had an arrhythmic event (AE).

Objectives: To conduct the first nationwide survey focused on BrS patients with documented AE.

Methods: Israeli electrophysiology units participated if they had treated BrS patients who had cardiac arrest (CA) (lethal/aborted; group 1) or experienced appropriate therapy for tachyarrhythmias after prophylactic implantable cardioverter defibrillator (ICD) implantation (group 2).

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Background: Elderly patients are underrepresented in clinical trials of device therapy.

Objective: To provide real-world data regarding outcomes associated with device-based therapy in a large cohort of elderly patients enrolled in the Israeli ICD Registry.

Methods: Between July 2010 and June 2012, a total of 2807 consecutive patients undergoing implanted cardioverter-defibrillator/cardiac resynchronization therapy-defibrillator (ICD/CRT-D) implantation were prospectively enrolled in the Israeli ICD Registry.

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Aim: Severe tricuspid insufficiency (TI) after permanent pacemaker implantation (PPI) has been described in small series of patients, though its incidence is not known.

Methods: We retrospectively analyzed the data of 545 patients who underwent PPI and had Doppler echocardiograms performed before and after the procedure. We excluded 135 patients who had > or =moderate TI on the 1st Doppler echocardiogram.

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Background: Conduction disturbances requiring permanent pacemaker implantation after heart surgery occur in about 1.5% of patients. Early pacemaker implantation may reduce morbidity and postoperative hospital stay.

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Background: Many electrophysiologists recommend implantable cardioverter defibrillators for patients with Brugada syndrome who are cardiac arrest survivors or presumed at high risk of sudden death (patients with syncope or a familial history of sudden death or those with inducible ventricular fibrillation at electrophysiologic study).

Objectives: To assess the efficacy and complications of ICD therapy in patients with Brugada syndrome.

Methods: The indications, efficacy and complications of ICD therapy in all patients with Brugada syndrome who underwent ICD implantation in 12 Israeli centers between 1994 and 2007 were analyzed.

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Background: New conduction disturbances requiring pacemaker implantation occur in about 1-3% of patients undergoing heart surgery. We reviewed our experience with patients undergoing heart surgery between the years 1993-2005 in order to identify predictors for pacemaker requirement.

Methods: There were 4999 patients aged 64 +/- 12 years.

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Background: Radiofrequency ablation has been suggested as first-line therapy in the management of accessory pathways. There are limited data on the results of ablation over years of experience.

Objectives: To assess the results and complications following RFA of APs performed in our institution over a 14 year period.

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