Publications by authors named "Michael Apel"
Article Synopsis
- The introduction highlights the rapid growth of point-of-care (POC) manufacturing for chimeric antigen receptor (CAR) modified T cells, particularly focusing on anti-CD20 CAR T cells for melanoma patients in a phase I clinical trial.
- The methods used involved producing CD20 CAR T cells using a second-generation lentiviral vector on the CliniMACS Prodigy® platform, demonstrating high purity and functionality across two production sites.
- Results confirmed a sufficient expansion and activation capability of the CAR T cells, revealing interindividual differences in their response, thereby supporting the effectiveness of the CliniMACS Prodigy® for decentralized CAR T cell manufacturing.
A new species of porcellanid crab, Petrolisthes tuerkayi n. sp., is described from the Persian Gulf.
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