In Cardiogenic Shock, Overweight and Obesity Have the Lowest, Whereas Cachexia Has the Highest Mortality.

The obesity paradox has been observed in patients with cardiovascular disease. The goal of this study was to evaluate whether obesity has a protective effect in patients presenting with cardiogenic shock. Using a large Nationwide Inpatient (NIS) sample database, we evaluated mortality in patients with cardiogenic shock based on weight categories in adults.

Variation in the treatment of pediatric lateral condyle fractures of the humerus: a survey of Pediatric Orthopedic Society of North America members.

Level III - survey study.

Weight Categories Have no Impact on Mortality in Patients Treated with Extracorporeal Membrane Oxygenation (ECMO).

BackgroundExtracorporeal Membrane Oxygenation (ECMO) is a critical support system for patients with acute and severe cardiac and respiratory failure. This study investigates the impact of different patient body weight categories on the mortality rates of patients undergoing ECMO support.MethodsUsing the Nationwide Sample (NIS) database and ICD-10 codes for 2016 to 2020 in adults over age 18, we evaluated total mortality based on weight categories compared to normal weights using univariate and multivariate analyses.

Evaluating the Association Between Systemic Treatments for Moderate to Severe Psoriasis and SARS-CoV-2 Infection Outcomes.

Moderate to severe psoriasis is often treated with systemic medications, including traditional therapies (eg, methotrexate, cyclosporine) and biologics (eg, TNF inhibitors, IL-17 and IL-23 inhibitors). These immunomodulating treatments raise concerns about infection risks, particularly during the SARS-CoV-2 pandemic. However, literature on systemic therapy and COVID-19 outcomes in the United States is limited.

High Mortality and Complications in Patients Admitted With Takotsubo Cardiomyopathy With More Than Double Mortality in Men Without Improvement in Outcome Over the Years.

Background: Takotsubo cardiomyopathy continues to be a major cause of mortality and morbidity. The goal of this study was to evaluate the outcome data of patients with Takotsubo cardiomyopathy using a large inpatient database.

Methods And Results: We used the Nationwide Inpatient Sample database for our study.

The Impact of Weight Categories on the Association Between Atrial Fibrillation/Flutter and Known Risk Factors: A Nationwide Inpatient Data Analysis.

: Atrial fibrillation and atrial flutter (Afib/Aflut) are the most common arrhythmias presenting to the emergency department. The goal of this study was to evaluate any predictor of Afib/flut with cardiovascular risk factors and demographics based on weight categories. : Using ICD-10 codes from the large Nationwide Inpatient Sample (NIS) database in the years 2016-2020, we evaluate any association between the presence of Afib/Aflut with risk factors and demographics in different weight categories in adults over the age of 18.

Mortality With Impella Is Lowest in Overweight and Obese but Is Highest in Morbid Obesity.

Introduction: Mortality of cardiogenic shock remains high, prompting increased use of mechanical circulatory support devices such as Impella. This study sought to characterize whether weight categories predict mortality in patients who received Impella devices.

Methods: We used data from the National Inpatient Sample (NIS) database from the years 2016 to 2020 and ICD-10-CM/PCS codes to evaluate the effect of weight categories on mortality in patients undergoing Impella implantation.

Partial obesity paradox regarding mortality in patients hospitalized with diastolic or systolic heart failure.

Introduction: A phenomenon known as the obesity paradox has been reported in patients with heart failure (HF). The goal of this study is to characterize this observation in systolic (SHF) and diastolic (DHF) HF.

Methods And Results: We used the National Inpatient Sample (NIS) database for 2016-2020.

Bodyweight affects mortality in an L-shape pattern in patients undergoing coronary bypass grafting.

Background: The role of body composition as a risk factor for adverse outcomesduring coronary artery bypass surgery (CABG) has been controversial. The goal of this study was to evaluate the effect of body weight on mortality in patients undergoing CABG.

Method: Using a large NIS database and ICD-10 coding for different bodyweight categories, we evaluated the effect of cachexia, overweight, obesity, and morbid obesity on in-hospital mortality after CABG.

Women with Breast Implants Have Higher Adjusted Abnormal Cardiac Testing and Coronary Angiography but Lower Coronary Intervention.

Background: Breast implants interfere with myocardial perfusion imaging (single photon emission computed tomography) and echocardiographic windows, leading to increased false-positive results. To validate this concept, we hypothesized that patients with breast implants should have higher positive cardiac testing and coronary angiogram with lower percutaneous coronary intervention (PCI) rates compared with women without a breast implant.

Methods: Using International Classification of Diseases, 10th Revision codes for breast implants, abnormal results of cardiac functional study, coronary angiogram, and PCIs, we evaluated any association between these parameters in adult women with breast implants utilizing the National Inpatient Sample database.

The use of intravascular ultrasound during percutaneous coronary intervention does not reduce all cause in-hospital mortality but doubles the cost, with higher utilization in privately insured patients.

Introduction: The effect of using intravascular ultrasound (IVUS) during percutaneous coronary intervention (PCI) on short-term mortality is not well established.

Aim: To evaluate any association between the use of IVUS vs. no IVUS during PCI and mortality in a large inpatient database.

In Patients Presenting with an ST-Elevation Myocardial Infarction, Overweight and Obese Patients Have the Lowest Inpatient Mortality whereas Cachexia Patients Have the Highest Inpatient Mortality Followed by Patients with Morbid Obesity.

The obesity paradox has been observed in patients with cardiovascular disease. The goal of this study was to evaluate whether obesity has a protective effect in patients presenting with an ST elevation myocardial infarction (STEMI). Using the large Nationwide Inpatient (NIS) sample database, we evaluated the mortality in patients with a STEMI based on weight categories.

Major depression is not associated with higher myocardial infarction rates: insights from a large database.

Depression has been suggested to increase the risk of cardiovascular disease, but many studies assessed depression after heart disease onset. This study evaluated the association between depression and myocardial infarction (MI) using a large inpatient database. We analyzed patients from the National Inpatient Sample hospitals from 2005 to 2020, selecting those aged >30 with ICD-9 and ICD-10 codes for segment elevation (ST) elevation myocardial infarction (STEMI), non-ST elevation myocardial elevation (NSTEMI) and major depression.

Higher post procedural bleeding in patients with advanced chronic kidney disease undergoing percutaneous coronary intervention.

Background: Advanced chronic kidney disease (ACKD) is common in patients undergoing percutaneous coronary intervention (PCI). Post-PCI bleeding has been shown to increase mortality and remains an important challenge in these patients. Previous studies have shown increased post-PCI bleeding in CKD patients but often ACKD patients are excluded from these trials.

The occurrence of ST elevation myocardial infarction (STEMI) and non-STEMI in patients with post traumatic stress disorder (PTSD) using the large nationwide inpatient sample (NIS).

Background: PTSD leads to increased levels of stress hormones and dysregulation of the autonomic nervous system which may trigger cardiac events. The goal of this study is to evaluate any association between PTSD and the occurrence of STEMI and NSTEMI using a large database.

Method: Using the Nationwide Inpatient Sample (NIS) and ICD-9 codes from 2005 to 2014 (n=1,621,382), we performed a univariate chi-square analysis of in-hospital occurrence of STEMI and NSTEMI in patients greater than 40 years of age with and without PTSD.

Percutaneous coronary intervention involving coronary bifurcation is associated with higher mortality and complications.

Background: Percutaneous coronary intervention (PCI) in patients with bifurcation lesions is associated with higher complexity and adverse outcomes. The goal of this study was to evaluate the inpatient outcomes of patients with PCI of bifurcation lesions.

Methods: The National Inpatient Sample (NIS) database, years 2016-2020, was studied using ICD 10 codes.

Coronary Perforation Occurring During Percutaneous Coronary Intervention Is Associated With Persistently High Mortality and Complications.

Introduction: Coronary perforation is one of the major complications of percutaneous coronary intervention (PCI). The goal of this study was to evaluate adverse outcomes and mortality in patients suffering from coronary perforation during PCI above the age of 30.

Methods: The National Inpatient Sample database, years 2016-2020, was studied using International Classification of Diseases, Tenth Revision codes.

In Patients with Cardiogenic Shock, Extracorporeal Membrane Oxygenation Is Associated with Very High All-Cause Inpatient Mortality Rate.

The goal of this study was to evaluate the effect of extracorporeal membrane oxygenation (ECMO) on mortality in patients with cardiogenic shock excluding Impella and IABP use. The large Nationwide Inpatient Sample (NIS) database was utilized to study any association between the use of ECMO in adults over the age of 18 and mortality and complications with a diagnosis of cardiogenic shocks. ICD-10 codes for ECMO and cardiogenic shock for the available years 2016-2020 were utilized.

Do breast implants not cause an increased rate of abnormal electrocardiograms (ECG)?

Background: Breast implants interfere may interfere with surface ECG recording. The goal of this study was to evaluate if the presence of breast implants can lead to abnormal electrocardiogram (ECG) using a large database in adults.

Methods: Using ICD 10 codes for breast implants and abnormal ECG, we evaluated any association between abnormal ECG coding in adult women with breast implants compared to women without breast implants utilizing the National Inpatient Sample (NIS) database.

Higher inpatient mortality following percutaneous coronary intervention in patients with advanced chronic kidney disease.

Background: Advanced chronic kidney disease (ACKD) is common in patients undergoing percutaneous coronary intervention (PCI) and is associated with adverse outcomes. These patients are often excluded from revascularization studies. The goal of this study was to evaluate the impact of ACKD in patients undergoing PCI.

Intra-aortic balloon pump is associated with the lowest whereas Impella with the highest inpatient mortality and complications regardless of severity or hospital types.

Impella and intra-aortic balloon pumps (IABP) are commonly utilized in patients with cardiogenic shock. However, the effect on mortality remains controversial. The goal of this study was to evaluate the effect of Impella and IABP on mortality in patients with cardiogenic shock the large Nationwide Inpatient Sample (NIS) database was utilized to study any association between the use of IABP or Impella on outcome.

Aortic regurgitation is associated with African American and Asian race, smoking, renal disease, and numerous autoimmune diseases in addition to traditional cardiovascular risk factors but has lower risk with alcohol intake.

Background: Aortic regurgitation (AR) is associated with increasing age, rheumatic heart disease, and a bicuspid aortic valve, but its association with other comorbidities and race is less known. The purpose of this study was to investigate any association between AR and comorbid conditions in older adults above 40.

Method: The large Nationwide Inpatient Sample database was utilized for our study using uni- and multivariate analysis.

Association between Factor-V Leiden and occurrence of acute myocardial infarction using a large NIS database.

Unlabelled: Factor V Leiden is an inheritable pro-thrombotic genetic condition caused by a point mutation at the 506 codon, resulting in activated protein C resistance. APC resistance has been shown to contribute to the development of venous thrombosis. However, the role of FVL in AMI has yet to be well defined in the current literature.

Lower myocardial infarction and all-cause mortality with laparoscopic cholecystectomy compared with open cholecystectomy.

We compared inpatient outcome data of open (OC) versus laparoscopic cholecystectomy (LC). We used the National Inpatient Samples database from 2010-2014. LC was done in 340,999 and OC in 68,529 OC patients.

Gender-based Disparity in Performing Aortic Valve Surgery in the United State Before Availability of Percutaneous Valve Implantation.

Background: Aortic valve surgery has been performed increasingly in high-risk patients. The goal of this study was to evaluate this trend based on gender in the United States before the availability of percutaneous aortic valve replacement.

Method: The Nationwide Inpatient Sample database was utilized to calculate the age-adjusted utilization rate for aortic valve surgery from 1988 to 2011 in the United States using International Classification of Diseases, Ninth Revision coding for aortic valve surgery.