Ganglion cell layer changes following the idiopathic macular hole surgery using inverted limiting membrane flap technique.

Purpose: The purpose of this study is to compare the ganglion cell layer changes following temporal inverted internal limiting membrane flap (i-ILMF) surgery for idiopathic macular hole (IMH).

Methods: This retrospective study included 50 eyes that underwent vitrectomy with a 2.5-disc-diameter temporal inverted internal limiting membrane flap (i-ILMF) technique.

The role of MRI patterns in predicting neurologic deficits in spinal ependymomas.

Objective: Spinal ependymomas are the most common intramedullary spinal cord tumors, with surgical resection being the primary treatment modality. This study aimed to evaluate the prognostic value of preoperative MRI features in predicting motor deficits in patients undergoing surgery for spinal ependymomas.

Methods: We retrospectively analyzed 71 patients with histopathologically confirmed spinal ependymomas who underwent surgical resection between 2009 and 2021.

The results of subthreshold 577 nm yellow laser application using pascal laser system in patients with chronic central serous chorioretinopathy.

To report the results of Endpoint Management (EpM) with PASCAL laser in the treatment of chronic central serous retinopathy (CSR). A 577 nm yellow laser was applied using PASCAL with EpM to 11 eyes on 11 patients who were followed for CSR for at least 12 months in this prospective study. The laser spot size was set to 200 μm, the pulse duration was 15 msec, and the spot spacing was set to 0.

Endophthalmitis following intravitreal injections at a tertiary center: real-life data on incidence, risk factors, management strategies, and visual outcomes.

Purpose: To investigate the incidence, contributing factors, management, and long-term outcomes of endophthalmitis following intravitreal injections performed in our clinic.

Methods: This retrospective study included all patients who received intravitreal bevacizumab, aflibercept, ranibizumab, or dexamethasone injections between 2019 and 2024 at four retina clinics of Ankara Bilkent City Hospital. Demographic characteristics of the patients, visual acuity, intravitreal injection etiology, comorbidities, and treatments applied were recorded.

Osteoplastic Pterional Craniotomy: Success Rate of Surgery in Patient Aspect.

Aim: To evaluate the effect of osteoplastic pterional craniotomy on temporal hollowing and its sequelae.

Material And Methods: A total of 97 patients who underwent pterional craniotomy for an aneurysm were analyzed retrospectively. Of these 97 patients, 63 underwent surgery via the conventional pterional approach and 34 underwent surgery via the osteoplastic pterional approach.

Investigation of boron adsorption by graphene oxide: equilibrium, kinetic, and thermodynamic studies.

Graphene oxide, which has a great application in industry, is one of the promising carbonous materials. Modified Hummers method was applied to synthesize graphene oxide. Characterization techniques showed that pure graphene oxide was successfully obtained.

Real Life Multicenter Comparison of 24-Month Outcomes of Anti-VEGF Therapy in Diabetic Macular Edema in Turkey: Ranibizumab vs. Aflibercept vs. Ranibizumab-Aflibercept Switch.

The aim of this study was to compare the outcomes of diabetic macular edema (DME) treated with aflibercept (AFB) or ranibizumab (RNB) only, and after switching from RNB to AFB. This was a retrospective, real-world, multicenter (7 cities) 24 month study. Overall, 212 eyes in the AFB group, 461 in the RNB group, and 141 in the RNB to AFB group were included.

Short-Term Results of Simpson Grade 2 Resection in Spinal Meningiomas.

Background: Spinal meningiomas are benign and slow-growing intradural tumors. Surgery is the choice of treatment. In this retrospective study, results of minimally invasive Simpson grade 2 resection and its impact on recurrence in 44 spinal meningiomas are reviewed.

Comparison of clinical and radiological results of dynamic and rigid instrumentation in degenerative lumbar spinal stenosis.

Objective: Lumbar spinal stenosis is defined as a clinical syndrome characterized by neurogenic claudication or radicular pain due to the narrowing of the spinal canal or neural foramen and the compression of its neural elements. Surgical treatment is applied to decompress the neural structures. In some cases, transpedicular instrumentation and fusion may also be applied.

Results of percutaneous cervical vertebroplasty using an anterolateral approach for cervical spine tumors.

Objective: The aim of this study was to report the results of percutaneous vertebroplasty in managing symptomatic osteolytic cervical spine tumors.

Methods: This study comprised a retrospective examination of patients who received percutaneous vertebroplasty between 2008 and 2020 for the treatment of tumor-induced symptomatic cervical vertebra involvement. The study summarized the demographics, vertebral levels, pain control rates, clinical results, and complications of percutaneous vertebroplasty using an anterolateral approach.

Anti-vascular endothelial growth factor therapy in diabetic macular edema: real-life outcomes from a multicenter study in Turkey over 36 months.

Purpose: This study aimed to report the visual and anatomical outcomes of intravitreal anti-VEGF treatment for diabetic macular edema (DME) in a real-world clinical setting from Turkey over 36 months.

Methods: This is a retrospective, multicenter (7 sites) study. The medical records of 1072 eyes (both previously treated and naive eyes) of 706 consecutive patients with visual impairment due to center-involving DME treated with intravitreal anti-VEGF injections between April 2007 and February 2017 were reviewed.

Management of Spinal Lymphomas: Spinal Instability Assessment Using the Spinal Instability Neoplastic Score and a Proposed Treatment Algorithm.

Aim: To propose a treatment algorithm, and to assess spinal instability in patients diagnosed with spinal lymphoma.

Material And Methods: Demographics, symptoms, tumor level and location, and presence of spinal instability were reviewed in 22 patients with spinal lymphomas. Each patient's neurological state was reviewed using the American Spinal Injury Association and modified McCormick scale scores, and spinal instability was assessed using the Spinal Instability Neoplastic Score (SINS).

Impact on Visual Acuity in Neovascular Age Related Macular Degeneration (nAMD) in Europe Due to COVID-19 Pandemic Lockdown.

This is a retrospective, multicenter study of consecutive patients with nAMD scheduled for a visit and/or a treatment with an intravitreal injection (IVI) during the 3 months before lockdown in the Ophthalmology Departments of six centers of Europe.The study was conducted on 546 patients, of which 55.13% were females, almost 100% of the patients were White/Caucasian race, and 71.

Bone-to-bone ligament preserving laminoplasty technique for reconstruction of laminae.

Introduction: Laminoplasty is a method used in spinal intradural tumor surgery to reduce the possibility of iatrogenic deformity. In classic laminoplasty, the interspinous, supraspinous, and ligamentum flavum integrity may be impaired, thereby creating a risk of deformity despite the laminoplasty. The aim of this study was to review the outcomes of bone-to-bone ligament preserving laminoplasty (BLP laminoplasty) technique.

Pediatric age, posterior fossa meningioma.

Meningiomas are benign, slow-growing tumors originating from arachnoid gap cells. They constitute 15%-20% of all intracranial tumors in adults and 04%-4% in the pediatric age group. Meningiomas in the posterior fossa in the pediatric period do not initially come to mind.

Lamina Measurements with Computed Tomography for C2 Translaminar Screw Fixation in Pediatric and Adult Cases.

Aim: To measure C2-related morphometric parameters in a Turkish population.

Material And Methods: The computed tomography (CT) images of three groups (Group 1: paediatric cases aged 1-6 years, Group 2: age7-16 years, and Group 3: adult cases), who had cervical spine CT were used to measure some morphometric parameters for safe C2 translaminar screw fixation. The measured parameters included thickness, height and length of the C2 lamina on both sides and the C2 lamina-midline angle.

Spinal Hemangioblastomas and Neuropathic Pain.

Background: Spinal hemangioblastomas (SHs) are rare and benign tumors. Primary symptoms include pain, hypoesthesia, and neuropathic pain (NP). Clinical symptoms may be as a result of tumor mass effect, peritumoral effect, syrinx, or venous congestion.

X-Linked Retinoschisis in Females in a Consanguineous Family: A Rare Entity.

X-linked juvenile retinoschisis (XLRS) is a disease considered characteristic for males. In this study we report a consanguineous family in which 3 daughters were diagnosed with XLRS. Typical signs of XLRS were detected in 2 girls, aged 4 and 15.

A Simple Cost-Effectiveness Analysis of Bilateral Decompression via Unilateral Approach versus Instrumented Total Laminectomy and Fusion for Lumbar Spinal Stenosis.

Aim: To compare the clinical and economic results of two different surgical approaches (bilateral decompression via unilateral approach and instrumented total laminectomy and fusion) in the treatment of lumbar spinal stenosis.

Material And Methods: The clinical, surgical, and economic aspects of 100 surgically treated patients with lumbar spinal stenosis were retrospectively reviewed.

Results: Decompression was performed at 158 levels in 100 patients.

Spinal Subarachnoid Hemorrhage Induced Intractable Miotic Pupil. A Reminder of Ciliospinal Sympathetic Center Ischemia Based Miosis: An Experimental Study.

Aim: To examine ischemic neurodegeneration of the ciliospinal center on permanent miosis following subarachnoid hemorrhage (SAH).

Material And Methods: Nineteen rabbits were examined in this study. The animals were divided into three groups, as control (GI, n=5), sham (GII, n=5) and study group (GIII, n=9).

Penetrating keratoplasty in patients with traumatic corneal scarring.

Background: To evaluate the results of penetrating keratoplasty (PK) due to trauma-related corneal scarring.

Methods: We evaluated 24 eyes of 24 patients who underwent PK due to trauma-related scarring of the cornea between May 2010 and June 2016. The postoperative visual acuity, graft transparency, and complications were evaluated.

The Use of Intraoperative Ultrasonography in Intradural Spinal Tumor Surgery.

Aim: To review our experience gained from the use of intraoperative ultrasonography (IOUSG) in intradural spinal tumor surgery.

Material And Methods: IOUSG was used during surgery of 69 intradural spinal tumors, operated on between 2012 and 2016. A 5-8 MHz probe of IOUSG was used, before and after durotomy to perform the exact durotomy and myelotomy, and after tumor resection, to detect a residual tumor.

Understanding of Dry Eye in Subarachnoid Hemorrhage: An Experimental Study on the Role of Facial Nerve Ischemia.

Aim: To understand possible mechanisms underlying lacrimal gland degeneration when facial nerve root ischemia induces pterygopalatine ganglion injury and subsequent dry eye in a rabbit model of subarachnoid hemorrhage.

Material And Methods: Rabbits were divided into four groups: control, sham, moderate subarachnoid hemorrhage, and severe subarachnoid hemorrhage. Autologous blood recovered from the auricular artery was injected into the cisterna magna to induce subarachnoid hemorrhage in the two subarachnoid hemorrhage groups; animals were then monitored for dry eye development over 21 days before removal of their facial nerve roots, pterygopalatine ganglia, and lacrimal glands for immunohistochemical analyses.

Nontraumatic Myositis Ossificans as an Uncommon Cause of Scoliosis: Case Report and Review of the Literature.

Background: A 5-year-old pediatric patient developed scoliosis associated with nontraumatic myositis ossificans in the lumbar region. Although there have been reports in literature of syndromes leading to widespread muscle ossifications resulting in shoulder deformities owing to impaired movement in the facet joints, to the best of our knowledge there has been no report of scoliosis associated with myositis ossificans.

Case Description: The case presented is of a 5-year-old girl who developed scoliosis associated with nontraumatic myositis ossificans in the lumbar region.

The optical coherence tomography angiography findings of rheumatoid arthritis patients taking hydroxychloroquine.

Purpose: The aim of this study is to measure retinal vessel density and thickness of the macula by optical coherence tomography angiography in patients with rheumatoid arthritis taking hydroxychloroquine.

Methods: The study included 40 patients with rheumatoid arthritis taking hydroxychloroquine and 20 age-, gender-, and axial length-matched control subjects. Patients were divided into two groups according to the duration of hydroxychloroquine use.