Reducing NICU ventilator days by preventing fluid overload with the CAN-U-P-LOTS standardized bundle.

Background: Fluid overload in critically ill neonates and infants is associated with higher ventilation days, prolonged length of stay, and mortality.

Methods: This quality improvement study enrolled infants admitted to Children's of Alabama NICU (excluding those with tracheostomies, severe congenital kidney or heart disease, DNR status, or severe genetic conditions). We compared 7 months of pre-intervention data (211 neonates) with 7 months of post-implementation data (218 neonates).