Publications by authors named "Md Rashedur Rahman Refat"
Biomed Res Int
April 2024
Article Synopsis
- Bacterial dysentery, particularly in developing countries, poses a serious health threat, worsened by the rise of multidrug-resistant strains that make treatment difficult due to limited healthcare access.
- This study analyzed the whole genome sequences (WGS) of pathogenic bacteria to identify antibiotic resistance genes (ARGs) and their mechanisms, revealing 2,146 ARGs across 45 genomes and highlighting the importance of antibiotic efflux pumps and target alterations in resistance.
- Key findings identified 13 hub proteins linked to resistance mechanisms, suggesting that understanding these proteins and ARGs is crucial for developing new therapeutic strategies against antibiotic-resistant strains.
