Publications by authors named "Md Imrul Hasan Chowdhury"

Article Synopsis
  • - Shigella is a major cause of shigellosis in developing countries like Bangladesh, where sanitation is poor, and antibiotics are the main treatment since no effective vaccine exists.
  • - A systematic review analyzed 28 studies involving over 44,000 samples in Bangladesh, revealing high rates of antibiotic resistance: fluoroquinolone (61.9%), trimethoprim-sulfamethoxazole (60.8%), and multi-drug resistance (33.4%).
  • - To combat the rising antibiotic resistance and improve treatment for shigellosis, there's a need for careful antibiotic use, better infection control, and ongoing monitoring of antibiotic effectiveness.
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Prickle2 has been identified in genetic studies of subjects with autism spectrum disorder (ASD) and epilepsy, but the pathological mechanism of Prickle2 remains to be fully understood. Proteomic analysis of Prickle2 with mass spectrometry revealed twenty-eight Prickle2 interactors, including immunoglobulin superfamily member 9b (Igsf9b), in the brain. Here, because Igsf9 family proteins are associated with psychiatric diseases and seizures, we studied the physiological interaction between Prickle2 and Igsf9b.

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