Publications by authors named "Mazen Zaher"

Trigeminal neuralgia (TN) is typically caused by neurovascular compression (NVC) at the root entry zone, often involving the superior cerebellar artery. Occasionally, TN may be secondary to cerebellopontine angle (CPA) tumors, such as meningiomas, vestibular schwannomas, or epidermoid cysts. When both a tumor and a vascular loop contribute to nerve compression, the resulting, as we refer to the "double crush" phenomenon, complicates surgical management and necessitates a more comprehensive therapeutic strategy.

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Background: External ventricular drains (EVDs) provide an invaluable diagnostic method for accessing cerebrospinal fluid and therapeutically treating elevated intracranial pressure. Although complications including hemorrhage and infection have been well documented, the formation of iatrogenic pseudoaneurysms following EVD placement has rarely been reported. The authors present a case of this exceedingly rare complication of iatrogenic pseudoaneurysm formation following EVD placement.

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Article Synopsis
  • Giant pituitary prolactinomas can cause rare but severe symptoms, such as acute hypoglossal nerve palsy and neurological decline, as highlighted in a case study of a 62-year-old woman with such a condition.
  • The patient experienced a syncopal episode and difficulties with speech and swallowing, leading to imaging that identified a giant apoplectic pituitary tumor.
  • Urgent surgery to decompress and reduce the tumor resulted in significant improvement in her symptoms, demonstrating the potential benefits of timely surgical intervention and the need for ongoing monitoring.
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Background: Posttraumatic seizures (PTSs) are a major source of disability after traumatic brain injury (TBI). The Brain Trauma Foundation Guidelines recommend prophylactic anti-epileptics (AEDs) for early PTS in severe TBI, but high-quality evidence is lacking in mild TBI.

Methods: To determine the benefit of administering prophylactic AEDs, we performed a prospective and multicenter study evaluating consecutive patients who presented to a Level 1 trauma center from January 2017 to December 2020.

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Background: Surgical management of brainstem cavernous malformations (CMs) is a controversial topic in the field of neurosurgery. These lesions have a propensity to hemorrhage, thereby disrupting surrounding brainstem eloquence.

Methods: This article provides the personal reflections of the senior author and a narrative literature review on resection of brainstem CMs.

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Severe meningitis, especially basilar meningitis, can lead to hydrocephalus requiring external ventricular drain (EVD) placement. There are differences in cerebrospinal fluid (CSF) obtained from an EVD compared to a lumbar puncture (LP). Hence, it becomes difficult to compare LP and EVD samples for diagnosis and monitoring of meningitis.

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