Focal Cerebral Injury in Pediatric Extracorporeal Life Support: Timing in Relation to Cannulation or Other Circuit Events in a Single-Center Retrospective Series, 2015-2023.

Objectives: To review the timing of extracorporeal life support (ECLS)-related focal cerebral injury (FCI) in relation to circuit interruptions in children and young adults.

Design: Retrospective study from January 1, 2015, to December 31, 2023.

Setting: Single-center academic children's hospital.

A Quantitative Electroencephalographic Index for Stroke Detection in Adults.

Purpose: Electroencephalography (EEG) remains underutilized for stroke characterization. We sought to assess the performance of the EEG Correlate Of Injury to the Nervous system (COIN) index, a quantitative metric designed for stroke recognition in children, in discriminating large from small ischemic strokes in adults.

Methods: Retrospective, single-center cohort of adults with acute (within 7 days) ischemic stroke who underwent at least 8 hours of continuous EEG monitoring in hospital.

Prevalence and Determinants of Prehospital Impression of Stroke in Ischemic Stroke Patients.

Background: Emergency Medical Services (EMS) clinicians are front-line in evaluating patients with stroke in the community. Their ability to correctly identify stroke influences downstream management decisions. We sought to use a large national database of prehospital clinical data to determine risk factors associated with missed EMS stroke identification.

A quantitative EEG index for the recognition of arterial ischemic stroke in children.

Objective: To describe and assess performance of the Correlate Of Injury to the Nervous system (COIN) index, a quantitative electroencephalography (EEG) metric designed to identify areas of cerebral dysfunction concerning for stroke.

Methods: Case-control study comparing continuous EEG data from children with acute ischemic stroke to children without stroke, with or without encephalopathy. COIN is calculated continuously and compares EEG power between cerebral hemispheres.

Neurological manifestations of polyarteritis nodosa: a tour of the neuroaxis by case series.

Background: Heterogenous central nervous system (CNS) neurologic manifestations of polyarteritis nodosa (PAN) are underrecognized. We review three cases of patients with PAN that illustrate a range of nervous system pathology, including the classical mononeuritis multiplex as well as uncommon brain and spinal cord vascular manifestations.

Case Presentation: Case 1 presented with mononeuritis multiplex and characteristic skin findings.

Epilepsy or a Seizure Disorder? Parental Knowledge and Misconceptions About Terminology.

Objective: To assess primary caregiver understanding of the term epilepsy.

Study Design: A cross-sectional telephone survey evaluated understanding of the term epilepsy among primary caregivers of children diagnosed with epilepsy at an urban referral center during a 24-month period. Three measures of primary caregiver understanding were used: (1) identifying if their child had a seizure disorder, epilepsy, or both; (2) providing an open-ended definition of epilepsy; and (3) selecting from a multiple-choice definition of epilepsy.

Acute Ataxia in Children: A Review of the Differential Diagnosis and Evaluation in the Emergency Department.

Acute ataxia in a pediatric patient poses a diagnostic dilemma for any physician. While the most common etiologies are benign, occasional individuals require urgent intervention. Children with stroke, toxic ingestion, infection, and neuro-inflammatory disorders frequently exhibit ataxia as an essential-if not the only-presenting feature.