J Allergy Clin Immunol Pract
July 2025
Background: Uncontrolled asthma in childhood is associated with exacerbations and impaired health-related quality of life. Commonly used control tools for children aged 5-11 years assess asthma symptoms but not exacerbations, potentially leading to overestimation of control and suboptimal management.
Objective: This cross-sectional observational study aimed to validate the Pediatric Asthma Impairment and Risk Questionnaire (Peds-AIRQ), a novel control tool assessing symptom impairment and exacerbation risk.
Background: Significant perinatal health disparities exist between people with and without disability in the United States and Canada. However, less is known about the perinatal healthcare experiences of people with different types of disability in those countries. Understanding this experience is crucial for developing tailored interventions to improve perinatal health outcomes.
View Article and Find Full Text PDFAnn Allergy Asthma Immunol
February 2025
Background: Asthma in children is a leading cause of missed school days, emergency department visits, and hospitalizations. Approximately 40% of children with asthma experience uncontrolled disease and annual exacerbations. There is a need for a validated composite tool for children, such as the Asthma Impairment and Risk Questionnaire (AIRQ), which was developed to assess current control and predict exacerbations in adolescents and adults with asthma.
View Article and Find Full Text PDFAm J Respir Crit Care Med
February 2025
There is increasing interest in the use of home-based monitoring in people with chronic lung diseases to improve access to care, support patient self-management, and facilitate the collection of information for clinical care and research. However, integration of home-based monitoring into clinical and research settings requires careful consideration of test performance and other attributes. There is no published guidance from professional respiratory societies to advance the science of home-based monitoring for chronic lung disease.
View Article and Find Full Text PDFAnn LGBTQ Public Popul Health
September 2024
Sexual minority (SM) adults have a higher prevalence of risk factors for cardiovascular disease (CVD), largely attributable to increased exposure to minority stressors. There are no evidence-based CVD risk reduction interventions tailored to the needs of SM adults. We conducted a qualitative descriptive study to explore SM adults' perceptions and preferences for a culturally tailored, minority stress-informed intervention for CVD risk reduction.
View Article and Find Full Text PDFBackground: Surrogates of incapacitated patients in the intensive care unit (ICU) face decisions related to life-sustaining treatments. Decisional conflict is understudied.
Objectives: To compare experiences of ICU surrogates by reported level of decisional conflict related to treatment decisions after a patient's cardiac arrest preceding death.
Background: Older adults from specific racial and ethnic minoritized groups experience disproportionately higher asthma prevalence, morbidity, and mortality. They also often use emergency departments (EDs) to manage their asthma. High-quality primary care can improve asthma control and prevent ED use.
View Article and Find Full Text PDFJ Allergy Clin Immunol Pract
August 2024
Background: Complex models combining impairment-based control assessments with clinical characteristics and biomarkers have been developed to predict asthma exacerbations. The composite Asthma Impairment and Risk Questionnaire (AIRQ) with adjustments for demographics (age, sex, race, and body mass index) predicts 12-month exacerbation occurrence similarly to these more complex models.
Objective: To examine whether AIRQ exacerbation prediction is enhanced when models are adjusted for a wider range of clinical characteristics and biomarkers.
Background: Nurse practitioners (NPs) increasingly deliver primary care in the United States. Yet, poor working conditions strain NP care. We examined whether racial/ethnic health disparities in ED visits among older adults with asthma are moderated by primary care NP work environments.
View Article and Find Full Text PDFAnn Allergy Asthma Immunol
July 2024
Background: National and international asthma guidelines and reports do not include control tools that combine impairment assessment with exacerbation history in one instrument.
Objective: To analyze the performance of the composite Asthma Impairment and Risk Questionnaire (AIRQ) in assessing both domains of control and predicting exacerbation risk compared with the Global Initiative for Asthma (GINA) 4-question symptom control tool (GINA SCT), Asthma Control Test (ACT), and physician expert opinion (EO) informed by GINA SCT responses and appraisal of GINA-identified risk factors for poor asthma outcomes.
Methods: Multivariable logistic regressions evaluated AIRQ and GINA SCT as predictors of ACT.
Ann Allergy Asthma Immunol
August 2024
Background: The Asthma Impairment and Risk Questionnaire (AIRQ) is a 10-item, yes/no, equally weighted control tool. Lower scores indicate better control. Moreover, 7 impairment items reflect previous 2-week symptoms, and 3 risk items assess previous 12-month exacerbations.
View Article and Find Full Text PDFJ Allergy Clin Immunol Pract
April 2024
Prevention of asthma exacerbations and reduction of systemic corticosteroid burden remain unmet needs in asthma. US asthma guidelines recommend concomitant short-acting β-agonist (SABA) and inhaled corticosteroid (ICS) as an alternative reliever at step 2. The Food and Drug Administration approved a pressurized metered-dose inhaler containing albuterol and budesonide for as-needed treatment or prevention of bronchoconstriction and for reducing exacerbation risk in patients with asthma aged ≥18 years.
View Article and Find Full Text PDFCurr Allergy Asthma Rep
November 2023
Purpose Of Review: A modified Delphi process was undertaken to provide a US expert-led consensus to guide clinical action on short-acting beta-agonist (SABA) use. This comprised an online survey (Phase 1), forum discussion and statement development (Phase 2), and statement adjudication (Phase 3).
Recent Findings: In Phase 1 (n = 100 clinicians), 12% routinely provided patients with ≥4 SABA prescriptions/year, 73% solicited SABA use frequency at every patient visit, and 21% did not consult asthma guidelines/expert reports.
Objective: To identify predictors of change in lung function and body weight during health care transition in cystic fibrosis (CF).
Methods: We conducted a retrospective cohort study using data from the CF Foundation Patient Registry and the web-based transition program CF RISE (Responsibility. Independence.
Objective: To pilot test an infographic-based health communication intervention that our team rigorously designed and explore whether its implementation leads to better health outcomes among Latino persons with HIV (PWH).
Materials And Methods: Latino PWH (N = 30) living in New York City received the intervention during health education sessions at 3 study visits that occurred approximately 3 months apart. At each visit, participants completed baseline or follow-up assessments and laboratory data were extracted from patient charts.
Transition from pediatric to adult care for adolescents and young adults (AYAs) with chronic illness affects the entire family. However, little research has compared AYA and parent experiences of transition. Using Sandelowski and Barroso's method, the aim of this metasynthesis was to summarize findings of qualitative studies focusing on the transition experiences of AYAs and their parents across different chronic physical illnesses.
View Article and Find Full Text PDFJ Allergy Clin Immunol Pract
November 2023
Background: Adolescents with cystic fibrosis (CF) and their parents must navigate changing roles and responsibilities within the family including transfer of disease management responsibilities.
Aim/objective: The aim of this qualitative study was to explore how families share and transfer CF management responsibility from the perspectives of adolescents with CF and their parents.
Methods: Guided by qualitative descriptive methodology, we purposively sampled adolescent/parent dyads.
Purpose: The identification of risk factors associated with uncontrolled moderate-to-severe asthma is important to improve asthma outcomes. Aim of this study was to identify risk factors for uncontrolled asthma in United States cohort using electronic health record (EHR)-derived data.
Patients And Methods: In this retrospective real-world study, de-identified data of adolescent and adult patients (≥12 years old) with moderate-to-severe asthma, based on asthma medications within 12 months prior to asthma-related visit (index date), were extracted from the Optum Humedica EHR.
J Allergy Clin Immunol Pract
September 2023
Background: With the expanding treatment landscape for asthma, the process of identifying best-fit, individualized management options is becoming increasingly complicated. Understanding patients' preferences can inform shared decision-making between clinicians and patients.
Objectives: To examine preferences of adults with asthma for therapeutic and management attributes and determine how these preferences vary among patients.
Background: Transgender and nonbinary (TGNB) populations experience high rates of hazardous drinking (HD) and alcohol use disorder (AUD) as well as unique treatment barriers. This is due, in-part, to discrimination and stigma within and outside of the healthcare system. Cultural adaptation of clinical interventions can improve outcomes for marginalized populations, but no such adapted interventions exist for AUD among TGNB individuals.
View Article and Find Full Text PDFAnn Allergy Asthma Immunol
October 2023
Background: Asthma control is often overestimated in routine practice, and despite advances in the understanding of immunopathology and the availability of new precision therapies, the burden of disease remains unacceptably high.
Objective: To compare the performance of the Asthma Impairment and Risk Questionnaire (AIRQ) with patient and physician assessments and the Asthma Control Test (ACT) in identifying asthma control.
Methods: Baseline data from a longitudinal study of the AIRQ were analyzed.
Objectives: To characterize perspectives and experiences regarding preconception care (PCC) patient education among women with type 2 diabetes.
Method: Descriptive, qualitative research design. Thirty-two English-speaking women with type 2 diabetes identifying as Black and/or Latina, ages 18-40 years old, participated.