Associations of event-related brain potentials and Alzheimer's disease severity: A longitudinal study.

Background: So far, no cost-efficient, widely-used biomarkers have been established to facilitate the objectivization of Alzheimer's disease (AD) diagnosis and monitoring. Research suggests that event-related potentials (ERPs) reflect neurodegenerative processes in AD and might qualify as neurophysiological AD markers.

Objectives: First, to examine which ERP component correlates the most with AD severity, as measured by the Mini-Mental State Examination (MMSE).

A Bayesian approach to analyzing phenotype microarray data enables estimation of microbial growth parameters.

Biolog phenotype microarrays (PMs) enable simultaneous, high throughput analysis of cell cultures in different environments. The output is high-density time-course data showing redox curves (approximating growth) for each experimental condition. The software provided with the Omnilog incubator/reader summarizes each time-course as a single datum, so most of the information is not used.