Speckled-egg staining appearance of cryptococcal osteomyelitis in an immunocompetent patient.

Introduction: Cryptococcal infections are typically thought of as occurring in immunocompromised patients, such as patients with HIV/AIDS, solid organ transplant recipients, or patients with rheumatologic diseases that require immunomodulatory therapy. Moreover, spp. classically appear as variably-sized yeasts with narrow-based budding surrounded by a thick polysaccharide capsule.